Results 151 to 160 of about 151,261 (309)

In Vitro Models For Cell-Based Cartilage Regeneration [PDF]

, 2014
__Abstract__ Covering the ends of the long bones in articular joints, cartilage allows smooth, gliding movement of the joints and distributes load evenly across the joint surface.
Vries-Van Melle, M.L. (Marloes) de
core  

Sacrificial strategy towards the formation of vascular‐like networks in volumetric tissue constructs

BMEMat, EarlyView.
This mini‐review highlights the latest progress in the sacrificial template‐enabled creation of patent vascular‐like networks, which can be incorporated into volumetric tissue constructs. Such microchannel networks can provide an immediate supply of nutrition and O2 to those cells residing next to the channels.
Christian Buckley, Rana Ibrahim, Felicia Giordano, Nuo Xu, Brandon Sems, Hongjun Wang   +5 more
wiley   +1 more source

New role of calcium‐binding fluorescent dye alizarin complexone in detecting permeability from articular cartilage to subchondral bone

FASEB BioAdvances
Osteoarthritis (OA) is a chronic degenerative joint disorder characterized by the progressive deterioration of articular cartilage and concomitant alterations in subchondral bone architecture. However, the precise mechanisms underlying the initiation and
Mingshu Cui, Mengcun Chen, Yanmei Yang, Hamza Akel, Bin Wang   +4 more
doaj   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Double-network acrylamide hydrogel compositions adapted to achieve cartilage-like dynamic stiffness [PDF]

, 2018
Since articular cartilage has a limited potential for spontaneous healing, various techniques are employed to repair cartilage lesions. Acrylate-based double-network (DN) hydrogels containing ~90% water have shown promising properties as repair materials
Arnold, M., Daniels, A., Gong, J., Kurokawa, T., Ronken, S., Wirz, D.   +5 more
core  

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Three‐dimensional assessment of subchondral arc and hip joint coverage angles in the asymptomatic young adult hip

Clinical Anatomy, EarlyView.
Abstract The primary objective of this study was to develop a custom algorithm to assess three‐dimensional (3D) acetabular coverage of the femoral head based on surface models generated from computed tomography (CT) imaging. The secondary objective was to apply this algorithm to asymptomatic young adult hip joints to assess the regional 3D acetabular ...
Holly D. Aitken, Jessica E. Goetz, Wyatt M. Sailer, Dominic J. L. Rivas, Christine L. Farnsworth, Vidyadhar V. Upasani, Joshua B. Holt   +6 more
wiley   +1 more source

Quantifying Knee Cartilage Shape and Lesion: From Image to Metrics [PDF]

arXiv
Imaging features of knee articular cartilage have been shown to be potential imaging biomarkers for knee osteoarthritis. Despite recent methodological advancements in image analysis techniques like image segmentation, registration, and domain-specific image computing algorithms, only a few works focus on building fully automated pipelines for imaging ...
arxiv  

Morphology of the sternoclavicular joint and its microanatomical changes in response to osteoarthritic degeneration

Clinical Anatomy, EarlyView.
Abstract Although the sternoclavicular joint shares structural similarities with the knee and hip joints as a diarthrodial joint, its biomechanics differ significantly due to its non‐weight‐bearing nature. Nevertheless, it is subject to considerable loading, leading to increased susceptibility to osteoarthritis, a prevalent condition characterized by ...
Sophie Mok, Yousef Almajed, Abdulaziz Alomiery, Roger Soames, Abduelmenem Alashkham   +4 more
wiley   +1 more source

Arthroscopic Evaluation of Knee Cartilage Using Optical Reflection Spectroscopy

Arthroscopy Techniques, 2019
Articular cartilage is critical for painless and low-friction range of motion; however, disruption of articular cartilage, particularly in the knee joint, is common.
Justin L. Makovicka, M.D., Karan A. Patel, M.D., Jeffrey D. Hassebrock, M.D., David E. Hartigan, M.D., Michael Wong, B.A., Anikar Chhabra, M.D.   +5 more
doaj