Results 11 to 20 of about 293,742 (284)
Focal lesions of articular cartilage give rise to pain and reduced joint function and may, if left untreated, lead to osteoarthritis. Implantation of in vitro generated, scaffold-free autologous cartilage discs may represent the best treatment option ...
Nadine Frerker +9 more
doaj +1 more source
THE PERMEABILITY OF ARTICULAR CARTILAGE [PDF]
1. We have shown that the permeability of cartilage is the same in necropsy specimens as in the living animal. We have concluded that studies of material transport into cartilage carried out on necropsy specimens validly reflect in vivo conditions. 2. We have studied the effect of agitation of the fluid in which cartilage is immersed upon the rate of
A, Maroudas +3 more
openaire +2 more sources
The effect of mechanical stress on the stiffness of articular cartilage and its role in the aetiology of osteoarthrosis [PDF]
Although a substantial amount is known about the pathogenesis of osteoarthrosis, its aetiology and in particular the role that mechanical factors play, remains unclear.
Swann, Anthony Charles
core +7 more sources
Vitrification of particulated articular cartilage via calculated protocols
Preserving viable articular cartilage is a promising approach to address the shortage of graft tissue and enable the clinical repair of articular cartilage defects in articulating joints, such as the knee, ankle, and hip.
Kezhou Wu +4 more
doaj +1 more source
CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes. [PDF]
To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter.
Shinsuke Itoh +6 more
doaj +1 more source
Functional repair of articular cartilage defects is always a great challenge in joint surgery clinically. Tissue engineering strategies that combine autologous cell implantation with three-dimensional scaffolds have proven effective for repairing ...
Litao Jia +7 more
doaj +1 more source
During the development of the appendicular skeleton, the cartilaginous templates undergo hypertrophic differentiation and remodels into bone, except for the cartilage most adjacent to joint cavities where hypertrophic differentiation and endochondral ...
Michael Chau +9 more
doaj +1 more source
The mechanical properties of biological tissues influence their function and can predict degenerative conditions before gross histological or physiological changes are detectable. This is especially true for structural tissues such as articular cartilage,
Katherine M. Arnold +3 more
doaj +1 more source
Cellular and molecular response to mechanical articular cartilage injury [PDF]
PhDJoint injures frequently involve structural damage to articular cartilage and the underlying subchondral bone. The outcome of acute joint surface defects (JSD) varies from spontaneous healing to the development of post-traumatic osteoarthritis (PTOA).
Eltawil, Noha
core +4 more sources
Contrast-enhanced micro-computed tomography (CEμCT) with phosphotungstic acid (PTA) has shown potential for detecting collagen distribution of articular cartilage.
Sakari S Karhula +8 more
doaj +1 more source

