Results 11 to 20 of about 293,742 (284)

Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Focal lesions of articular cartilage give rise to pain and reduced joint function and may, if left untreated, lead to osteoarthritis. Implantation of in vitro generated, scaffold-free autologous cartilage discs may represent the best treatment option ...
Nadine Frerker   +9 more
doaj   +1 more source

THE PERMEABILITY OF ARTICULAR CARTILAGE [PDF]

open access: yesThe Journal of Bone and Joint Surgery. British volume, 1968
1. We have shown that the permeability of cartilage is the same in necropsy specimens as in the living animal. We have concluded that studies of material transport into cartilage carried out on necropsy specimens validly reflect in vivo conditions. 2. We have studied the effect of agitation of the fluid in which cartilage is immersed upon the rate of
A, Maroudas   +3 more
openaire   +2 more sources

The effect of mechanical stress on the stiffness of articular cartilage and its role in the aetiology of osteoarthrosis [PDF]

open access: yes, 1988
Although a substantial amount is known about the pathogenesis of osteoarthrosis, its aetiology and in particular the role that mechanical factors play, remains unclear.
Swann, Anthony Charles
core   +7 more sources

Vitrification of particulated articular cartilage via calculated protocols

open access: yesnpj Regenerative Medicine, 2021
Preserving viable articular cartilage is a promising approach to address the shortage of graft tissue and enable the clinical repair of articular cartilage defects in articulating joints, such as the knee, ankle, and hip.
Kezhou Wu   +4 more
doaj   +1 more source

CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes. [PDF]

open access: yesPLoS ONE, 2013
To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter.
Shinsuke Itoh   +6 more
doaj   +1 more source

Acellular cartilage matrix biomimetic scaffold with immediate enrichment of autologous bone marrow mononuclear cells to repair articular cartilage defects

open access: yesMaterials Today Bio, 2022
Functional repair of articular cartilage defects is always a great challenge in joint surgery clinically. Tissue engineering strategies that combine autologous cell implantation with three-dimensional scaffolds have proven effective for repairing ...
Litao Jia   +7 more
doaj   +1 more source

The synovial microenvironment suppresses chondrocyte hypertrophy and promotes articular chondrocyte differentiation

open access: yesnpj Regenerative Medicine, 2022
During the development of the appendicular skeleton, the cartilaginous templates undergo hypertrophic differentiation and remodels into bone, except for the cartilage most adjacent to joint cavities where hypertrophic differentiation and endochondral ...
Michael Chau   +9 more
doaj   +1 more source

Atomic Force Microscopy Micro-Indentation Methods for Determining the Elastic Modulus of Murine Articular Cartilage

open access: yesSensors, 2023
The mechanical properties of biological tissues influence their function and can predict degenerative conditions before gross histological or physiological changes are detectable. This is especially true for structural tissues such as articular cartilage,
Katherine M. Arnold   +3 more
doaj   +1 more source

Cellular and molecular response to mechanical articular cartilage injury [PDF]

open access: yes, 2010
PhDJoint injures frequently involve structural damage to articular cartilage and the underlying subchondral bone. The outcome of acute joint surface defects (JSD) varies from spontaneous healing to the development of post-traumatic osteoarthritis (PTOA).
Eltawil, Noha
core   +4 more sources

Effects of Articular Cartilage Constituents on Phosphotungstic Acid Enhanced Micro-Computed Tomography.

open access: yesPLoS ONE, 2017
Contrast-enhanced micro-computed tomography (CEμCT) with phosphotungstic acid (PTA) has shown potential for detecting collagen distribution of articular cartilage.
Sakari S Karhula   +8 more
doaj   +1 more source

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