Results 41 to 50 of about 426,032 (330)
Scientific Reports, 2017 The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated ...
Yoshitoshi Higuchi +10 more
doaj +1 more source
Gels, 2021 Joint diseases that mainly lead to articular cartilage injury with prolonged severe pain as well as dysfunction have remained unexplained for many years.
Xu Han +4 more
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Come together over me: Cells that form the dermatocranium and chondrocranium in mice
The Anatomical Record, EarlyView., 2023 Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri +5 more
wiley +1 more source
Repair of Damaged Articular Cartilage: Current Approaches and Future Directions
International Journal of Molecular Sciences, 2018 Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor vascularized, and its low cell density allows only extremely limited self-renewal.
E. V. Medvedeva +6 more
semanticscholar +1 more source
Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo [PDF]
, 2013 INTRODUCTION: Signals from the epidermal growth factor receptor (EGFR) have typically been considered to provide catabolic activities in articular cartilage, and accordingly have been suggested to have a causal role in osteoarthritis progression. The aim
Caroline N Dealy +4 more
core +1 more source
Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9 [PDF]
, 2007 Objective. Human osteoarthritis (OA) is characterized by a pathologic shift in articular cartilage homeostasis toward the progressive loss of extracellular matrix (ECM).
Cucchiarini, Magali +5 more
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Frontiers in Bioengineering and Biotechnology, 2023 Objectives: This study aimed to investigate the morphological and mechanical changes in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs.Materials and methods: Hip joints of guinea pigs were investigated at 1,
Jiazi Gao, Pengling Ren, He Gong
doaj +1 more source
Three-Dimensional Bioprinting of Articular Cartilage: A Systematic Review
Cartilage, 2018 Objective Treatment of chondral injury is clinically challenging. Available chondral repair/regeneration techniques have significant shortcomings. A viable and durable tissue engineering strategy for articular cartilage repair remains an unmet need.
Yang Wu +5 more
semanticscholar +1 more source
Regulation of growth plate and articular chondrocyte differentiation : implications for longitudinal bone growth and articular cartilage formation [PDF]
, 2014 Overall height and body proportions in humans are determined primarily by bone growth. Linear bone growth occurs at the growth plate, a thin layer of cartilage at the ends of long bones between the epiphysis and metaphysis.
Chau, Michael
core +1 more source
Materials Today Bio, 2022 Functional repair of articular cartilage defects is always a great challenge in joint surgery clinically. Tissue engineering strategies that combine autologous cell implantation with three-dimensional scaffolds have proven effective for repairing ...
Litao Jia +7 more
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