Results 61 to 70 of about 502,749 (311)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Periosteum-covered ACI (ACI-P) versus collagen membrane ACI (ACI-C): A single-surgeon, large cohort analysis of clinical outcomes and graft survivorship

Journal of Cartilage & Joint Preservation, 2021
Introduction: Autologous chondrocyte implantation (ACI) has undergone several technical modifications. Objectives: To compare clinical outcomes and graft survivorship between ''first-generation'' periosteum-covered ACI (ACI-P) and ''second-generation ...
Liana Leja, MS, Tom Minas, MD, MS
doaj  

The effect of intervertebral cartilage on neutral posture and range of motion in the necks of sauropod dinosaurs [PDF]

, 2013
The necks of sauropod dinosaurs were a key factor in their evolution. The habitual posture and range of motion of these necks has been controversial, and computer-aided studies have argued for an obligatory sub-horizontal pose.
A Christian, BD Hultgren, CL Emerson, CM Holliday, CW Gilmore, D Schwarz, E Frey, EC McKenzie, G Dzemski, GS Paul, H Mallison, H Mallison, J Martin, JB Hatcher, JS McIntosh, K Carpenter, K Glass, K Stevens, KA Stevens, KE Whitwell, M Papageorges, Mathew J. Wedel, MF Bonnan, Michael P. Taylor, MJ Cobley, MJ Wedel, MJ Wedel, MJ Wedel, MJ Wedel, MJ Wedel, MP Taylor, MP Taylor, MP Taylor, NPH Hudson, OC Marsh, P Upchurch, PC Wagner, Peter Dodson, PM Sander, PP Vidal, RC Da Costa, RE Levitski, W Graf, W Janensch, WD Matthew, WM McKee   +45 more
core   +4 more sources

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Matrix-Associated Chondroplasty: A Novel Platelet-Rich Plasma and Concentrated Nucleated Bone Marrow Cell–Enhanced Cartilage Restoration Technique

Arthroscopy Techniques, 2014
Bone marrow stimulation techniques such as microfracture for the treatment of articular cartilage defects so far solely reproduce mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm.
Matthias R. Steinwachs, M.D., Bernhard Waibl, M.D., Stephanie Wopperer, M.D., Marcus Mumme, M.D.   +3 more
doaj  

Cartilage Restoration Using Dehydrated Allogeneic Cartilage, Platelet-Rich Plasma, and Autologous Cartilage Mixture Sealed With Activated Autologous Serum

Arthroscopy Techniques, 2020
Articular cartilage injury is a common source of knee pain and dysfunction. Patients in whom conservative treatment fails may benefit from surgical intervention to restore function and alleviate pain.
Tracy M. Tauro, B.S., B.A., Abbott Gifford, Eric D. Haunschild, B.S., Ron Gilat, M.D., Michael C. Fu, M.D., Brian J. Cole, M.D., M.B.A.   +5 more
doaj  

Altered Gut Microbiota as an Auxiliary Diagnostic Indicator for Patients With Fracture-Related Infection

Frontiers in Microbiology, 2022
Preoperative diagnosis of fracture-related infection (FRI) is difficult for patients without obvious signs of infection. However, specific profiles of gut microbiota may be used as a potential diagnostic tool for FRI as suggested by a previous study. The
Xingqi Zhao, Xingqi Zhao, Wenli Tang, Haoyang Wan, Haoyang Wan, Zixin Lan, Hanjun Qin, Hanjun Qin, Qingrong Lin, Qingrong Lin, Yanjun Hu, Yanjun Hu, Guangchuang Yu, Nan Jiang, Nan Jiang, Bin Yu, Bin Yu   +16 more
doaj   +1 more source

The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. [PDF]

, 2013
Osteoarthritis (OA) is a degenerative disease that affects various tissues surrounding joints such as articular cartilage, subchondral bone, synovial membrane, and ligaments.
Maldonado, Maricela, Nam, Jin
core   +3 more sources

Enhanced Mechanical Properties of Injectable Chitosan–Guar Gum Hydrogel Reinforced with Bacterial Cellulose Nanofibers for Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This study presents the development and characterization of injectable nanocomposite hydrogels based on N‐succinyl chitosan, oxidized guar gum, and bacterial cellulose nanofibers. Emphasizing enhanced mechanical properties and biocompatibility, the hydrogels exhibit fast gelation, improved structural integrity, and reduced swelling. Their potential for
Raimundo Nonato Fernandes Moreira Filho, Pascale Chevallier, Silvia Rodriguez Fernandez, Maud Viallon, Matheus Xavier de Oliveira, Ana Lorena de Brito Soares, Diego Mantovani, Judith Pessoa de Andrade Feitosa, Rodrigo Silveira Vieira   +8 more
wiley   +1 more source

Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel

Arthroscopy Techniques, 2014
Bone marrow stimulation techniques for the treatment of articular cartilage defects such as microfracture so far have solely reproduced mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm ...
Matthias R. Steinwachs, M.D., Bernhard Waibl, M.D., Marcus Mumme, M.D.   +2 more
doaj