Results 71 to 80 of about 502,749 (311)

Increased oxidative phosphorylation through pyruvate dehydrogenase kinase 2 deficiency ameliorates cartilage degradation in mice with surgically induced osteoarthritis

open access: yesExperimental and Molecular Medicine
Chondrocytes can shift their metabolism to oxidative phosphorylation (OxPhos) in the early stages of osteoarthritis (OA), but as the disease progresses, this metabolic adaptation becomes limited and eventually fails, leading to mitochondrial dysfunction ...
Jin Han, Yoon Hee Kim, Seungwoo Han
doaj   +1 more source

Nocturnal Changes in Knee Cartilage Thickness in Young Healthy Adults [PDF]

open access: yes, 2012
Magnetic resonance imaging (MRI) allows one to analyze cartilage physiology in vivo. Cartilage deforms during loading, but little is known about its recovery after deformation.
Eckstein, F.   +2 more
core   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

Chondrocyte Heterogeneity; It Is the Time to Update the Understanding of Cartilage Histology [PDF]

open access: yesSVU-International Journal of Veterinary Sciences (2018), 2018
Chondrocytes were described as one cell populations in most cartilage literature. Two different chondrocyte populations; dark and light, were described in the articular cartilage and a third population, adipochondrocytes, was described in the elastic cartilage.
arxiv  

Superlubricious Surfaces Through Surface Attached Hydrogels Obtained by C,H‐insertion Crosslinking

open access: yesAdvanced Functional Materials, EarlyView.
Taking synovial joints as a source of inspiration, the friction properties of surfaces covered with 1d‐swelling polyelectrolyte hydrogels in combination with a shear‐thinning aqueous lubricant are studied. Such systems obtained by C,H insertion crosslinking show superlubricious behavior, even surpassing the friction values reported for the natural ...
Renato Maraula   +5 more
wiley   +1 more source

Mini-open Subpectoral Biceps Tenodesis Using All-Suture Anchor

open access: yesArthroscopy Techniques, 2020
The proximal biceps tendon is a common source of shoulder pain and dysfunction. When patients continue to have pain after exhaustive nonoperative treatment, the long head of the biceps tendon can be effectively treated with a tenotomy or tenodesis ...
Abbott Gifford   +4 more
doaj  

Cartilage repair in the degenerative ageing knee: A narrative review and analysis

open access: yesActa Orthopaedica, 2016
Background and purpose — Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis.
Mats Brittberg   +5 more
doaj   +1 more source

Differentially Expressed Genes in Osteomyelitis Induced by Staphylococcus aureus Infection

open access: yesFrontiers in Microbiology, 2018
Osteomyelitis (OM) is a complicated and serious disease and its underlying molecular signatures of disease initiation and progression remain unclear. Staphylococcus aureus (S. aureus) is the most common causative agent of OM. Previous study of Banchereau
Peisheng Chen   +12 more
doaj   +1 more source

Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis. [PDF]

open access: yes, 2019
Osteoarthritis (OA), long considered a primary disorder of articular cartilage, is commonly associated with subchondral bone sclerosis. However, the cellular mechanisms responsible for changes to subchondral bone in OA, and the extent to which these ...
Acevedo, Claire   +12 more
core  

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

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