Results 81 to 90 of about 87,840 (204)

Diagnostic imaging of the canine stifle [PDF]

, 2012
C
Gielen, Ingrid, van Bree, Henri, Van Ryssen, Bernadette   +2 more
core   +1 more source

Intermittent intra-articular delivery of FGF8b enhances cartilage homeostasis and attenuates osteoarthritis progression

Journal of Orthopaedic Translation
Objective: Osteoarthritis (OA) is a chronic disease characterized by degeneration of articular cartilage, affecting over half a billion individuals globally. Current treatments such as non-steroidal anti-inflammatory drugs are effective in symptom relief,
Xiuqin Peng, Jiaming Han, Yu Tian, Xiaohong Li, Xuanqi Zhang, Song Li, Jun Yang, Liang Chen, Siru Zhou, Nan Su, Xueqin Mao, Bin Zhang, Hangang Chen, Jing Yang, Min Jin, Can Li, Wanling Jiang, Peng Liu, Yangli Xie, Liang Kuang, Lin Chen   +20 more
doaj   +1 more source

Correlation between Radiographic and Arthroscopic Findings in Asian Osteoarthritic Knees

Journal of Orthopaedic Surgery, 2014
Purpose. To evaluate the correlation between radiographic and arthroscopic findings for severity of knee osteoarthritis (OA) in 119 Asians. Methods.
Hamid Rahmatullah Bin Abd Razak, Hwee Yee Christian Heng, Ke Yi Cheng, Amit Kanta Mitra   +3 more
doaj   +1 more source

Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis

Arthritis Research & Therapy, 2018
Background ADAMTS aggrecanases play a major role in cartilage degeneration during degenerative and inflammatory arthritis. The cartilage-specific secreted protein Upper zone of growth plate and cartilage matrix associated protein (Ucma) has been shown to
Fritz Seuffert, Daniela Weidner, Wolfgang Baum, Georg Schett, Michael Stock   +4 more
doaj   +1 more source

A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system

International Journal of Nanomedicine, 2018
Shaowei Wang,1 Xiaochun Wei,1 Xiaojuan Sun,1 Chongwei Chen,1 Jingming Zhou,2 Ge Zhang,3 Heng Wu,3 Baosheng Guo,3 Lei Wei1,2 1Department of Orthopaedics, The 2nd Hospital of Shanxi Medical University, Taiyuan, Shanxi, China; 2Department of Orthopaedics ...
Wang S, Wei X, Sun X, Chen C, Zhou J, Zhang G, Wu H, Guo B, Wei L   +8 more
doaj  

N6‐Methyladenosine‐Modified circSMAD4 Prevents Lumbar Instability Induced Cartilage Endplate Ossification

Advanced Science
Lumbar instability causes cartilage endplate ossification and intervertebral disc degeneration. In this study, it is determined that circSMAD4, a Yap1‐related circRNA, is stably downregulated under abnormal stress.
Hanwen Li, Yingchuang Tang, Sihan Hu, Xingbang Ruan, Junxin Zhang, Yihan Shi, Liang Qiu, Huilin Yang, Kai Zhang, Hao Chen, Kangwu Chen   +10 more
doaj   +1 more source

Role of Galectin-3 in intervertebral disc degeneration: an experimental study

BMC Musculoskeletal Disorders
Background This study investigated the role of Galectin-3 in the degeneration of intervertebral disc cartilage. Methods The patients who underwent lumbar spine surgery due to degenerative disc disease were recruited and divided into Modic I, Modic II ...
Jianjiang Li, Nianrong Han, Zhenqiang Liu, Akram Osman, Leilei Xu, Jing Song, Yang Xiao, Wei Hu   +7 more
doaj   +1 more source

Injectable decellularized Wharton's jelly hydrogel containing CD56+ umbilical cord mesenchymal stem cell-derived exosomes for meniscus tear healing and cartilage protection

Materials Today Bio
Traditional meniscectomy or suture for meniscal tear usually leads to failed self-healing, cartilage degeneration and worse osteoarthritis. The strategies that facilitate the healing process of torn meniscus and safeguard knee cartilage against ...
Simiao Kang, Xin Shi, Yong Chen, Lin Zhang, Quanbo Liu, Ziyang Lin, Hongbin Lu, Haile Pan   +7 more
doaj   +1 more source

Injury-related cell death and proteoglycan loss in articular cartilage: Numerical model combining necrosis, reactive oxygen species, and inflammatory cytokines

PLoS Computational Biology, 2023
Osteoarthritis (OA) is a common musculoskeletal disease that leads to deterioration of articular cartilage, joint pain, and decreased quality of life. When OA develops after a joint injury, it is designated as post-traumatic OA (PTOA).
Joonas P. Kosonen, Atte S. A. Eskelinen, Gustavo A. Orozco, Petteri Nieminen, Donald D. Anderson, Alan J. Grodzinsky, Rami K. Korhonen, Petri Tanska   +7 more
doaj  

Dual‐Modular Hydrogel Microparticles with Precision‐Modulation of Inflammatory Microenvironment Dictate Full‐Thickness Cartilage Regeneration for Osteoarthritis Repair

Advanced Science
Osteoarthritis (OA) is a typical degenerative disease characterized primarily by the degeneration of cartilage. However, current treatments for cartilage degeneration often lead to the formation of hypertrophic cartilage and fibrocartilage, making it ...
Xinye Chen, Yuanman Yu, Zirui He, Lina Pan, Jing Wang, Changsheng Liu   +5 more
doaj   +1 more source