Results 131 to 140 of about 116,755 (297)

Acoustic emission diagnosis for human joint cartilage diseases

, 2015
Purpose: The topic of the presented paper concerns the diagnosis of the wear and diseases of human joint cartilage performed by the acoustic waves emission.
Wierzcholski, K.
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

NGF-BMSC-SF/CS composites for repairing knee joint osteochondral defects in rabbits: evaluation of the repair effect and potential underlying mechanisms

Journal of Orthopaedic Surgery and Research
Background With the rapid growth of the ageing population, chronic diseases such as osteoarthritis have become one of the major diseases affecting the quality of life of elderly people.
Yong Zhang, Wenliang Huang, Hongli Xiao, Shiqiang Ruan, Jiang Deng   +4 more
doaj   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Articular Cartilage: Structure, Composition, Injuries and Repair

, 2018
[[abstract]]Articular cartilage has a unique structure that makes it very different from any other tissues in the body. It has such specific roles and functions such as weight bearing with low frictional coefficient that the main bulk of its structure is
Ng, Hooi Yee;Ng, Hooi Yee;Alv, Kai-Xing;Lee, Kai-Xing Alvin;沈育芳;Shen, Yu-Fang
core  

Sonoelastographic Evaluation Of The Distal Femoral Cartilage In Patients With Anterior Cruciate Ligament Reconstruction

, 2016
Objectives: This study aims to evaluate sonoelastographic properties of the distal femoral cartilage in patients with anterior cruciate ligament (ACL) reconstruction. Patients and methods: Demographic characteristics and operative data of 28 patients (27
Gungor, Harun R., Ağladıoğlu, Kadir, Agladioglu, Kadir, Ok, Nusret, Akkaya, Semih, Güngör, Harun Reşit, Akkaya, Nuray., Ozcakar, Levent, Özçakar, Levend, Akkaya, Nuray   +9 more
core   +1 more source

Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Advanced Science, EarlyView.
Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F. Duarte Campos   +5 more
wiley   +1 more source

The Potential of Pulsed Low Intensity Ultrasound to stimulate Chondrocytes in a 3D Model System

, 2009
PhDPulsed low intensity ultrasound (PLIUS) is used clinically to accelerate fracture healing. although the mode of action is unclear. However studies suggest that PLIUS may stimulate endochondral ossification and consequently PLIUS may also be ...
Vaughan, Natalie Marlene
core  

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Potential strategies for effective utilization of costal cartilage in articular cartilage injury repair

European Cells & Materials
Background: Joint diseases are one of the leading causes of global disability. Various methods of cartilage repair, including microfracture, mosaic chondroplasty, and autologous chondrocyte transplantation, have been actively studied.
SA Sheleg, AD Kurenkova, ZA Mosina, PS Timashev   +3 more
doaj   +1 more source