Results 11 to 20 of about 108,199 (280)
Matrix Biol, 2018 Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human body including bearing loads in articular joints and intervertebral discs, providing joint lubrication, forming the external ears and nose, supporting the trachea, and forming the long bones during development and growth.
Krishnan Y, Grodzinsky AJ.
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Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities [PDF]
International Journal of Molecular Sciences, 2022 Cartilage oligomeric matrix protein (COMP) is an extracellular matrix (ECM) glycoprotein that is critical for collagen assembly and ECM stability. Mutations of COMP cause endoplasmic reticulum stress and chondrocyte apoptosis, resulting in rare skeleton diseases.
Jiarui Cui, Jiaming Zhang
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Stem Cells in Cartilage Diseases and Repair 2018 [PDF]
Stem Cells International, 2018 Jianying Zhang +4 more
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Gels, 2021 Joint diseases that mainly lead to articular cartilage injury with prolonged severe pain as well as dysfunction have remained unexplained for many years.
Xu Han +4 more
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PTPN11 in cartilage development, adult homeostasis, and diseases
Bone ResearchThe SH2 domain-containing protein tyrosine phosphatase 2 (SHP2, also known as PTP2C), encoded by PTPN11, is ubiquitously expressed and has context-specific effects.
Wentian Yang, Véronique Lefebvre
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Cartilage of I-Cell Disease [PDF]
Pediatric Research, 1981 Biochemical analysis and morphologic observation of the iliac crest cartilage from 8-year-old girl with I-cell disease were performed. Instead of hypertrophic change of chondrocytes in the zone of cartilage-bone junction, there were small atrophic cells having many inclusion bodies accumulated with lamellar materials.
H, Nogami +3 more
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Exercise improves subchondral bone microenvironment through regulating bone-cartilage crosstalk
Frontiers in Endocrinology, 2023 Articular cartilage degeneration has been proved to cause a variety of joint diseases, among which osteoarthritis is the most typical. Osteoarthritis is characterized by articular cartilage degeneration and persistent pain, which affects the quality of ...
Shihua Zhang +9 more
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Osteochondral explant for cartilage research: a promising tool linking bench to bedside [PDF]
European Cells & Materials, 2022 Diarthrodial joint diseases, affecting hundreds of millions of people worldwide, mainly include osteoarthritis and cartilage injuries. No consensus on joint disease models has been achieved so far owing to the complex aetiologies, pathophysiological ...
KH Li +5 more
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Melatonin: Effects on Cartilage Homeostasis and Therapeutic Prospects in Cartilage-related Diseases [PDF]
Aging and disease, 2021 Cartilage is a relatively simple connective tissue that plays a variety of roles in the human body, including joint support and protection, load bearing of the intervertebral discs, joint lubrication, formation of the external structure of the ears and nose and support of the trachea.
Xie, Wen-qing +7 more
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Cartilage tissue engineering for degenerative joint disease☆ [PDF]
Advanced Drug Delivery Reviews, 2006 Pain in the joint is often due to cartilage degeneration and represents a serious medical problem affecting people of all ages. Although many, mostly surgical techniques, are currently employed to treat cartilage lesions, none has given satisfactory results in the long term.
Nesic, Dobrila +5 more
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