Results 11 to 20 of about 9,103,182 (195)
Cartilage tissue engineering for degenerative joint disease☆ [PDF]
Advanced Drug Delivery Reviews, 2006 Pain in the joint is often due to cartilage degeneration and represents a serious medical problem affecting people of all ages. Although many, mostly surgical techniques, are currently employed to treat cartilage lesions, none has given satisfactory results in the long term.
Dobrila Nešić +5 more
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Cartilage homeostasis in health and rheumatic diseases [PDF]
Arthritis Research & Therapy, 2009 As the cellular component of articular cartilage, chondrocytes are responsible for maintaining in a low-turnover state the unique composition and organization of the matrix that was determined during embryonic and postnatal development. In joint diseases,
M. Goldring, K. Marcu
semanticscholar +4 more sources
Mesenchymal stem cells for cartilage regeneration
Journal of Tissue Engineering, 2020 Cartilage injuries are typically caused by trauma, chronic overload, and autoimmune diseases. Owing to the avascular structure and low metabolic activities of chondrocytes, cartilage generally does not self-repair following an injury. Currently, clinical
Hanxiang Le +5 more
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Runx2 and microRNA regulation in bone and cartilage diseases [PDF]
Annals of the New York Academy of Sciences, 2016 The homeostasis of skeletal tissues requires tight regulation of a variety of signaling pathways, and the onset and progression of skeletal diseases are often caused by signaling abnormalities. MicroRNAs (miRNAs) are short noncoding RNA molecules that have emerged as a new dimension of gene regulation.
Weiwei Zhao +5 more
semanticscholar +3 more sources
Regulation of Cartilage Development and Diseases by Transcription Factors [PDF]
Journal of Bone Metabolism, 2017 Genetic studies and molecular cloning approaches have been successfully used to identify several transcription factors that regulate the numerous stages of cartilage development.
R. Nishimura +5 more
semanticscholar +4 more sources
Role of Epigenomics in Bone and Cartilage Disease [PDF]
Journal of Bone and Mineral Research, 2019 ABSTRACT Phenotypic variation in skeletal traits and diseases is the product of genetic and environmental factors. Epigenetic mechanisms include information-containing factors, other than DNA sequence, that cause stable changes in gene expression and are maintained during cell divisions.
Joyce B. J. van Meurs +3 more
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MSC-EV therapy for bone/cartilage diseases
Bone Reports, 2022 Mesenchymal stromal cells (MSCs) have been utilized in cell therapy for various diseases. Recent studies have demonstrated that extracellular vesicles (EVs) released by MSCs play an important role in their therapeutic activities. EVs contain a variety of
Joe Kodama +2 more
doaj +3 more sources
THE TREATMENT OF DISEASES OF THE COSTAL CARTILAGES
Annals of Surgery, 1918 Alexis V. Moschcowitz
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Wnt signaling in cartilage development and diseases: lessons from animal studies [PDF]
Laboratory Investigation, 2015 Yu Usami +3 more
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P323 IS DISEASED CARTILAGE MORE HOMOGENOUS THAN HEALTHY CARTILAGE?
Osteoarthritis and Cartilage, 2006 A.A. Qazi +6 more
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