Results 21 to 30 of about 2,326,263 (272)
Strategies for Articular Cartilage Repair and Regeneration
Frontiers in Bioengineering and Biotechnology, 2021 Articular cartilage is an avascular tissue, with limited ability to repair and self-renew. Defects in articular cartilage can induce debilitating degenerative joint diseases such as osteoarthritis.
Yanxi Liu +3 more
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Use of Exogenous Hyaluronic Acid for the Treatment of Patellar Chondropathy– A Six-Month Randomized Controlled Trial [PDF]
Revista Brasileira de OrtopediaObjective To evaluate the clinical and radiological benefits of intra-articular exogenous hyaluronic acid for the treatment of chondral patellar injury. Method Randomized clinical trial with 70 patients divided into 2 groups: those submitted to physical
Diego Costa Astur +5 more
doaj +3 more sources
Sex-dependent variation in cartilage adaptation: from degeneration to regeneration
Biology of Sex Differences, 2023 Highlights Evidence indicates males and females respond differently to cartilage degeneration and regeneration. Few review articles available provide comprehensive information referencing clinical and laboratory research.
Jhanvee Patel +4 more
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Frontiers in Bioengineering and Biotechnology, 2021 In the mammalian skeletal system, osteogenesis and angiogenesis are closely linked by type H vessels during bone regeneration and repair. Our previous studies confirmed the promotion of these processes by copper-containing metal (CCM) in vitro and in ...
Daorong Xu +21 more
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Cartilage homeostasis in health and rheumatic diseases [PDF]
Arthritis Research & Therapy, 2009 As the cellular component of articular cartilage, chondrocytes are responsible for maintaining in a low-turnover state the unique composition and organization of the matrix that was determined during embryonic and postnatal development. In joint diseases, cartilage homeostasis is disrupted by mechanisms that are driven by combinations of biological ...
Goldring, Mary B, Marcu, Kenneth B
openaire +2 more sources
SOX9 in cartilage development and disease
Current Opinion in Cell Biology, 2019 SOX9 is a pivotal transcription factor in chondrocytes, a lineage essential in skeletogenesis. Its mandatory role in transactivating many cartilage-specific genes is well established, whereas its pioneer role in lineage specification, which along with transactivation defines master transcription factors, remains to be better defined.
Véronique, Lefebvre +2 more
openaire +3 more sources
Biomolecules, 2022 Epidemiological data suggest that various noncommunicable diseases develop as a result of altered maternal metabolic and physiological status due to exposure to several adverse factors during pregnancy. However, evidence for intrauterine exposure factors
Wenji Wang +4 more
doaj +1 more source
A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]
, 2009 Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul +2 more
core +1 more source
Osteoarthritis as a disease of the cartilage pericellular matrix [PDF]
Matrix Biology, 2018 Osteoarthritis is a painful joint disease characterized by progressive degeneration of the articular cartilage as well as associated changes to the subchondral bone, synovium, and surrounding joint tissues. While the effects of osteoarthritis on the cartilage extracellular matrix (ECM) have been well recognized, it is now becoming apparent that in many
Guilak, F. +4 more
openaire +3 more sources
Frontiers in Chemistry, 2021 Recently, as our population increasingly ages with more pressure on bone and cartilage diseases, bone/cartilage tissue engineering (TE) have emerged as a potential alternative therapeutic technique accompanied by the rapid development of materials ...
Yifeng Shi +10 more
doaj +1 more source