Results 21 to 30 of about 111,756 (251)
Use of Exogenous Hyaluronic Acid for the Treatment of Patellar Chondropathy– A Six-Month Randomized Controlled Trial [PDF]
Revista Brasileira de OrtopediaObjective To evaluate the clinical and radiological benefits of intra-articular exogenous hyaluronic acid for the treatment of chondral patellar injury. Method Randomized clinical trial with 70 patients divided into 2 groups: those submitted to physical
Diego Costa Astur +5 more
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Frontiers in Bioengineering and Biotechnology, 2021 In the mammalian skeletal system, osteogenesis and angiogenesis are closely linked by type H vessels during bone regeneration and repair. Our previous studies confirmed the promotion of these processes by copper-containing metal (CCM) in vitro and in ...
Daorong Xu +21 more
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Biomolecules, 2022 Epidemiological data suggest that various noncommunicable diseases develop as a result of altered maternal metabolic and physiological status due to exposure to several adverse factors during pregnancy. However, evidence for intrauterine exposure factors
Wenji Wang +4 more
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SOX9 in cartilage development and disease
Current Opinion in Cell Biology, 2019 SOX9 is a pivotal transcription factor in chondrocytes, a lineage essential in skeletogenesis. Its mandatory role in transactivating many cartilage-specific genes is well established, whereas its pioneer role in lineage specification, which along with transactivation defines master transcription factors, remains to be better defined.
Véronique, Lefebvre +2 more
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Osteoarthritis as a disease of the cartilage pericellular matrix [PDF]
Matrix Biology, 2018 Osteoarthritis is a painful joint disease characterized by progressive degeneration of the articular cartilage as well as associated changes to the subchondral bone, synovium, and surrounding joint tissues. While the effects of osteoarthritis on the cartilage extracellular matrix (ECM) have been well recognized, it is now becoming apparent that in many
Guilak, F. +4 more
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Frontiers in Chemistry, 2021 Recently, as our population increasingly ages with more pressure on bone and cartilage diseases, bone/cartilage tissue engineering (TE) have emerged as a potential alternative therapeutic technique accompanied by the rapid development of materials ...
Yifeng Shi +10 more
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Histone Modifications and Chondrocyte Fate: Regulation and Therapeutic Implications
Frontiers in Cell and Developmental Biology, 2021 The involvement of histone modifications in cartilage development, pathology and regeneration is becoming increasingly evident. Understanding the molecular mechanisms and consequences of histone modification enzymes in cartilage development, homeostasis ...
Chao Wan +12 more
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Nihon Kikai Gakkai ronbunshu, 2014 Articular cartilage has a poor ability to regenerate itself, therefore it is important to establish the treatment methodologies for cartilage diseases such as osteoarthritis (OA) or rheumatoid arthritis (RA).
Shinya YAMAZAKI, Shogo MIYATA
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lncRNAs: function and mechanism in cartilage development, degeneration, and regeneration
Stem Cell Research & Therapy, 2019 With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and intervertebral disc degeneration (IDD), heavier financial and social burdens need to be faced.
Jian Zhu +10 more
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Frontiers in Bioengineering and Biotechnology, 2022 Sandwiched between articular cartilage and subchondral bone, the calcified cartilage layer (CCL) takes on both biomechanical and biochemical functions in joint development and ordinary activities.
Weiyang Wang +11 more
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