Results 31 to 40 of about 116,755 (297)
Nihon Kikai Gakkai ronbunshu, 2014 Articular cartilage has a poor ability to regenerate itself, therefore it is important to establish the treatment methodologies for cartilage diseases such as osteoarthritis (OA) or rheumatoid arthritis (RA).
Shinya YAMAZAKI, Shogo MIYATA
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Biomechanical assessment of extracellular matrix in native and tissue engineered cartilage across lenght scales [PDF]
, 2012 Musculoskeletal diseases (MSD) and related disorders account for the largest fraction of temporary and permanent disabilities, and are often considered to be an inevitable consequence of aging.
Loparic, Marko
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Frontiers in Bioengineering and Biotechnology, 2022 Sandwiched between articular cartilage and subchondral bone, the calcified cartilage layer (CCL) takes on both biomechanical and biochemical functions in joint development and ordinary activities.
Weiyang Wang +11 more
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microRNAs in Cartilage Development, Homeostasis, and Disease [PDF]
Current Osteoporosis Reports, 2014 microRNAs (miRNAs) regulate gene expression mainly at the posttranscriptional level. Many different miRNAs are expressed in chondrocytes, and each individual miRNA can regulate hundreds of target genes, creating a complex gene regulatory network.
Fatemeh, Mirzamohammadi +2 more
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, 2008 Osteoarthritis (OA) is generally a disease of the elderly population, but can occur in young patients in exceptional cases. This study compares the cellular and epigenetic features of primary old-age OA with those of secondary OA in a 23-year old patient
da Silva, M.A. +3 more
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Cartilage to bone transitions in health and disease [PDF]
Journal of Endocrinology, 2013 Aberrant redeployment of the ‘transient’ events responsible for bone development and postnatal longitudinal growth has been reported in some diseases in what is otherwise inherently ‘stable’ cartilage. Lessons may be learnt from the molecular mechanisms underpinning transient chondrocyte differentiation and function, and their application may better ...
Staines, Katherine +4 more
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Cartilage tissue engineering for degenerative joint disease☆ [PDF]
Advanced Drug Delivery Reviews, 2006 Pain in the joint is often due to cartilage degeneration and represents a serious medical problem affecting people of all ages. Although many, mostly surgical techniques, are currently employed to treat cartilage lesions, none has given satisfactory results in the long term.
Nesic, Dobrila +5 more
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In major joint diseases the human synovium retains its potential to form repair cartilage [PDF]
, 2023 The inner surface layer of human joints, the synovium, is a source of stem cells for the repair of articular cartilage defects. We investigated the potential of the normal human synovium to form novel cartilage and compared its chondrogenic capacity with
Kurt Lippuner +9 more
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Investigation of the Effect of Selected Piperazine-2,5-Diones on Cartilage-Related Cells
Chemistry Proceedings, 2021 Various chronic inflammatory diseases have become a problem, especially in the Western world. Whether it concerns inflammation of visceral organs, joints, bones, etc., it is always a physiological reaction of the body, which always tries to eradicate ...
Josef Jampilek, Jan Hosek, Pavel Bobal
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, 2012 The structural anisotropy of articular cartilage controls its deformation response. As proteoglycans and collagen vary with depth, simple uniaxial compression results in inhomogeneous deformation with distinct depth-dependent mechanical properties ...
Szarko, M, Xia, Y
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