Results 51 to 60 of about 111,756 (251)

From cells to organs: progress and potential in cartilaginous organoids research

open access: yesJournal of Translational Medicine, 2023
While cartilage tissue engineering has significantly improved the speed and quality of cartilage regeneration, the underlying metabolic mechanisms are complex, making research in this area lengthy and challenging.
Xiao-he Wang   +4 more
doaj   +1 more source

Water loss and defects dependent strength and ductility of articular cartilage

open access: yesJournal of Materials Research and Technology, 2022
Water loss and surface defects of articular cartilage extremely aggravate the risk of osteoarticular diseases. The effects of water content and surface defects on the mechanical properties of cartilage need to be taken into further account.
Jize Liu   +5 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

open access: yesArthritis Care &Research, Accepted Article.
Objective VEXAS syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures. A VEXAS‐specific disease activity index (DAI) is an essential tool for reliably capturing changes in disease ...
Kevin Byram   +25 more
wiley   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Extrusion‐Based Additive Manufacturing of Advanced Ceramics: Strengthening Mechanisms and Process Optimization Review

open access: yesAdvanced Engineering Materials, EarlyView.
This review comprehensively evaluates extrusion‐based additive manufacturing for advanced ceramics, detailing feedstock options and key process parameters. By critically addressing defect mechanisms like porosity and cracking, the work highlights optimization strategies through machine learning and advanced postprocessing.
Meisam Bakhtiari   +4 more
wiley   +1 more source

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

open access: yesSmall Science
With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health.
Yao Wang   +3 more
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Application of Cord Blood and Cord Blood-Derived Induced Pluripotent Stem Cells for Cartilage Regeneration

open access: yesCell Transplantation, 2019
Regeneration of articular cartilage is of great interest in cartilage tissue engineering since articular cartilage has a low regenerative capacity. Due to the difficulty in obtaining healthy cartilage for transplantation, there is a need to develop an ...
Yeri Alice Rim, Yoojun Nam, Ji Hyeon Ju
doaj   +1 more source

iCartiGD: the Integrated Cartilage Gene Database

open access: yesBMC Genetics, 2007
Background Diseases of cartilage, such as arthritis and degenerative disc disease, affect the majority of the general population, particularly with ageing.
Sham Pak   +10 more
doaj   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei   +9 more
wiley   +1 more source

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