Results 71 to 80 of about 116,755 (297)

Joint contact modelling of articular cartilage in synovial joints [PDF]

open access: yes, 2010
Hip joint is one of the important load bearing joints and has been extensively studied to investigate contact mechanics and tribology. It has known to experience high contact forces and stresses.
ath Shrikant, Sainath Shrikant   +1 more
core  

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Application of Cord Blood and Cord Blood-Derived Induced Pluripotent Stem Cells for Cartilage Regeneration

open access: yesCell Transplantation, 2019
Regeneration of articular cartilage is of great interest in cartilage tissue engineering since articular cartilage has a low regenerative capacity. Due to the difficulty in obtaining healthy cartilage for transplantation, there is a need to develop an ...
Yeri Alice Rim, Yoojun Nam, Ji Hyeon Ju
doaj   +1 more source

iCartiGD: the Integrated Cartilage Gene Database

open access: yesBMC Genetics, 2007
Background Diseases of cartilage, such as arthritis and degenerative disc disease, affect the majority of the general population, particularly with ageing.
Sham Pak   +10 more
doaj   +1 more source

A low percentage of autologous serum can replace bovine serum to engineer human nasal cartilage [PDF]

open access: yes, 2008
For the generation of cell-based therapeutic products, it would be preferable to avoid the use of animal-derived components. Our study thus aimed at investigating the possibility to replace foetal bovine serum (FBS) with autologous serum (AS) for the ...
Farhadi, J.   +11 more
core  

Potential directions for drug development for osteoarthritis [PDF]

open access: yes, 2008
Background: osteoarthritis (OA) is a frustrating disease for both patient and physician because neither cause nor cure is known and there are currently no disease-modifying drugs.
Roach, Helmtrud I.
core   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

open access: yesAdvanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee   +3 more
wiley   +1 more source

Distribution of subchondral bone density and cartilage thickness in the human patella [PDF]

open access: yes, 1992
Subchondral bone density (by means of CT osteoabsorptiometry), and cartilage thickness (directly measured on photocopies of frozen sections), were examined in 30 human patellae, with an age range from 47 to 90 y.
Eckstein, Felix   +2 more
core  

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]

open access: yes, 2005
Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Uzan, Benjamin   +3 more
core   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

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