Results 31 to 40 of about 9,103,182 (195)

Cartilage to bone transitions in health and disease [PDF]

Journal of Endocrinology, 2013
Aberrant redeployment of the ‘transient’ events responsible for bone development and postnatal longitudinal growth has been reported in some diseases in what is otherwise inherently ‘stable’ cartilage. Lessons may be learnt from the molecular mechanisms underpinning transient chondrocyte differentiation and function, and their application may better ...
Staines, Katherine, Pollard, Andrea Sophie, McGonnell, Imelda M, Farquharson, Colin, Pitsillides, Andrew Anthony   +4 more
openaire   +4 more sources

Copper-Containing Alloy as Immunoregulatory Material in Bone Regeneration via Mitochondrial Oxidative Stress

Frontiers in Bioengineering and Biotechnology, 2021
In the mammalian skeletal system, osteogenesis and angiogenesis are closely linked by type H vessels during bone regeneration and repair. Our previous studies confirmed the promotion of these processes by copper-containing metal (CCM) in vitro and in ...
Daorong Xu, Daorong Xu, Jikun Qian, Jikun Qian, Xin Guan, Xin Guan, Ling Ren, Kaifan Yang, Kaifan Yang, Xuan Huang, Shuyuan Zhang, Yu Chai, Yu Chai, Xiaohu Wu, Xiaohu Wu, Hangtian Wu, Hangtian Wu, Xianrong Zhang, Xianrong Zhang, Ke Yang, Bin Yu, Bin Yu   +21 more
doaj   +1 more source

High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer

BioTechniques, 2014
Micromass cultures of primary embryonic limb mesenchyme are a valuable model system for studying cartilage formation in vitro. However, high efficiency introduction of plasmid DNA into this hard-to-transfect cell type typically results in considerable ...
Brent E. Bobick, Peter G. Alexander, Rocky S. Tuan   +2 more
doaj   +1 more source

Sex-dependent variation in cartilage adaptation: from degeneration to regeneration

Biology of Sex Differences, 2023
Highlights Evidence indicates males and females respond differently to cartilage degeneration and regeneration. Few review articles available provide comprehensive information referencing clinical and laboratory research.
Jhanvee Patel, Song Chen, Torey Katzmeyer, Yixuan Amy Pei, Ming Pei   +4 more
doaj   +1 more source

Progress of Microfluidic Hydrogel‐Based Scaffolds and Organ‐on‐Chips for the Cartilage Tissue Engineering

Advances in Materials, 2023
Cartilage degeneration is among the fundamental reasons behind disability and pain across the globe. Numerous approaches have been employed to treat cartilage diseases. Nevertheless, none have shown acceptable outcomes in the long run.
Hamidreza Tolabi, Niyousha Davari, Mehran Khajehmohammadi, Haniyeh Malektaj, Katayoun Nazemi, Samaneh Vahedi, B. Ghalandari, R. Reis, F. Ghorbani, J. Oliveira   +9 more
semanticscholar   +1 more source

Use of Exogenous Hyaluronic Acid for the Treatment of Patellar Chondropathy– A Six-Month Randomized Controlled Trial [PDF]

Revista Brasileira de Ortopedia
Objective To evaluate the clinical and radiological benefits of intra-articular exogenous hyaluronic acid for the treatment of chondral patellar injury. Method Randomized clinical trial with 70 patients divided into 2 groups: those submitted to physical
Diego Costa Astur, Felipe Berteli Angelini, Marcelo Abdulchlek Santos, Gustavo Gonçalves Arliani, Paulo Santoro Belangero, Moisés Cohen   +5 more
doaj   +3 more sources

The advances in nanomedicine for bone and cartilage repair

Journal of Nanobiotechnology, 2022
With the gradual demographic shift toward an aging and obese society, an increasing number of patients are suffering from bone and cartilage injuries.
Kai Qiao, Lu Xu, Junnan Tang, Qiguang Wang, K. Lim, G. Hooper, T. Woodfield, Guozhen Liu, Kang Tian, Weiguo Zhang, X. Cui   +10 more
semanticscholar   +1 more source

Effects of the Leptin-Mediated MAPK/ERK Signaling Pathway on Collagen II Expression in Knee Cartilage of Newborn Male Mice from Obese Maternal Offspring

Biomolecules, 2022
Epidemiological data suggest that various noncommunicable diseases develop as a result of altered maternal metabolic and physiological status due to exposure to several adverse factors during pregnancy. However, evidence for intrauterine exposure factors
Wenji Wang, Jialing Zhang, Yu Huo, Yuanzheng Zheng, Yonghao Gui   +4 more
doaj   +1 more source

Low-intensity pulsed ultrasound promotes mesenchymal stem cell transplantation-based articular cartilage regeneration via inhibiting the TNF signaling pathway [PDF]

Stem Cell Res Ther 14, 93 (2023), 2021
Background: Mesenchymal stem cell (MSC) transplantation therapy is highly investigated for the regenerative repair of cartilage defects. Low-intensity pulsed ultrasound (LIPUS) has the potential to promote chondrogenic differentiation of MSCs. However, its underlying mechanism remains unclear.
arxiv   +1 more source

Recent Developments in Hyaluronic Acid-Based Hydrogels for Cartilage Tissue Engineering Applications

Polymers, 2022
Articular cartilage lesions resulting from injurious impact, recurring loading, joint malalignment, etc., are very common and encompass the risk of evolving to serious cartilage diseases such as osteoarthritis.
Evgenia Tsanaktsidou, Olga Kammona, C. Kiparissides   +2 more
semanticscholar   +1 more source