Results 41 to 50 of about 9,103,182 (195)
Frontiers in Chemistry, 2021 Recently, as our population increasingly ages with more pressure on bone and cartilage diseases, bone/cartilage tissue engineering (TE) have emerged as a potential alternative therapeutic technique accompanied by the rapid development of materials ...
Yifeng Shi +10 more
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Bone-a-Petite: Engineering Exosomes towards Bone, Osteochondral, and Cartilage Repair.
Small, 2021 Recovery from bone, osteochondral, and cartilage injuries/diseases has been burdensome owing to the damaged vasculature of large defects and/or avascular nature of cartilage leading to a lack of nutrients and supplying cells.
H. Bei +4 more
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SOX9 in cartilage development and disease
Current Opinion in Cell Biology, 2019 SOX9 is a pivotal transcription factor in chondrocytes, a lineage essential in skeletogenesis. Its mandatory role in transactivating many cartilage-specific genes is well established, whereas its pioneer role in lineage specification, which along with transactivation defines master transcription factors, remains to be better defined.
Marco Angelozzi +2 more
openaire +3 more sources
Histone Modifications and Chondrocyte Fate: Regulation and Therapeutic Implications
Frontiers in Cell and Developmental Biology, 2021 The involvement of histone modifications in cartilage development, pathology and regeneration is becoming increasingly evident. Understanding the molecular mechanisms and consequences of histone modification enzymes in cartilage development, homeostasis ...
Chao Wan +12 more
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Oxidative Medicine and Cellular Longevity, 2018 Cartilage is essential for skeletal development by endochondral ossification. The only cell type within the tissue, the chondrocyte, is responsible for the production of macromolecules for the extracellular matrix (ECM). Before proteins and proteoglycans
Yvonne Rellmann, R. Dreier
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Sandwiched between articular cartilage and subchondral bone, the calcified cartilage layer (CCL) takes on both biomechanical and biochemical functions in joint development and ordinary activities.
Weiyang Wang +11 more
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Biophysical and biomechanical properties of cartilage [PDF]
arXiv, 2023 Cartilage is a connective tissue that covers the surfaces of bones in joints and provides a smooth gliding surface for movement. It is characterized by specific biophysical properties that allow it to withstand compressive loads, distribute mechanical forces, and maintain tissue integrity.
arxiv
lncRNAs: function and mechanism in cartilage development, degeneration, and regeneration
Stem Cell Research & Therapy, 2019 With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and intervertebral disc degeneration (IDD), heavier financial and social burdens need to be faced.
Jian Zhu +10 more
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Recent progress in cartilage lubrication [PDF]
arXiv, 2023 Healthy articular cartilage, covering the ends of bones in major joints such as hips and knees, presents the most efficiently-lubricated surface known in nature, with friction coefficients as low as 0.001 up to physiologically high pressures. Such low friction is indeed essential for its well being.
arxiv
Nihon Kikai Gakkai ronbunshu, 2014 Articular cartilage has a poor ability to regenerate itself, therefore it is important to establish the treatment methodologies for cartilage diseases such as osteoarthritis (OA) or rheumatoid arthritis (RA).
Shinya YAMAZAKI, Shogo MIYATA
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