Results 61 to 70 of about 9,103,182 (195)
Biomechanical Influence of Cartilage Homeostasis in Health and Disease [PDF]
Arthritis, 2011 There is an urgent demand for long term solutions to improve osteoarthritis treatments in the ageing population. There are drugs that control the pain but none that stop the progression of the disease in a safe and efficient way. Increased intervention efforts, augmented by early diagnosis and integrated biophysical therapies are therefore needed ...
D. L. Bader +2 more
openaire +5 more sources
The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies
Experimental and Molecular Medicine, 2020 As an essential nutrient and trace element, selenium is required for living organisms and its beneficial roles in human health have been well recognized.
Donghyun Kang +6 more
semanticscholar +1 more source
From cells to organs: progress and potential in cartilaginous organoids research
Journal of Translational Medicine, 2023 While cartilage tissue engineering has significantly improved the speed and quality of cartilage regeneration, the underlying metabolic mechanisms are complex, making research in this area lengthy and challenging.
Xiao-he Wang +4 more
doaj +1 more source
Animal Models and Experimental MedicineBackground Native cartilage has low capacity for regeneration because it has very few progenitor cells. Human umbilical cord blood‐derived mesenchymal stem cells (hUCB‐MSCs) and human umbilical cord‐derived MSCs (hUC‐MSCs) have been employed as promising
Xingfu Li, Zhenhan Deng, Wei Lu
doaj +1 more source
Polysaccharide-based hydrogels for cartilage regeneration
Frontiers in Cell and Developmental BiologyCartilage defect is one of the common tissue defect clinical diseases and may finally lead to osteoarthritis (OA) which threat patients’ physical and psychological health.
Ning Chen +6 more
doaj +1 more source
Quantitative predictive modelling approaches to understanding rheumatoid arthritis: A brief review [PDF]
, 2019 Rheumatoid arthritis is a chronic autoimmune disease that is a major public health challenge. The disease is characterised by inflammation of synovial joints and cartilage erosion, which leads to chronic pain, poor life quality and, in some cases, premature mortality.
arxiv +1 more source
iCartiGD: the Integrated Cartilage Gene Database
BMC Genetics, 2007 Background Diseases of cartilage, such as arthritis and degenerative disc disease, affect the majority of the general population, particularly with ageing.
Sham Pak +10 more
doaj +1 more source
Improving Robustness of Deep Learning Based Knee MRI Segmentation: Mixup and Adversarial Domain Adaptation [PDF]
, 2019 Degeneration of articular cartilage (AC) is actively studied in knee osteoarthritis (OA) research via magnetic resonance imaging (MRI). Segmentation of AC tissues from MRI data is an essential step in quantification of their damage. Deep learning (DL) based methods have shown potential in this realm and are the current state-of-the-art, however, their ...
arxiv +1 more source
Cell Transplantation, 2019 Regeneration of articular cartilage is of great interest in cartilage tissue engineering since articular cartilage has a low regenerative capacity. Due to the difficulty in obtaining healthy cartilage for transplantation, there is a need to develop an ...
Yeri Alice Rim, Yoojun Nam, Ji Hyeon Ju
doaj +1 more source
Journal of Cellular and Molecular Medicine, 2013 Cartilage has limited repair and regeneration capacity, thus damage of cartilage often results in its dysfunction and even chronic diseases like osteoarthritis (OA).
J. Shang, Huan Liu, Yue Zhou
semanticscholar +1 more source