Results 61 to 70 of about 136,745 (341)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Viability and tissue quality of cartilage flaps from patients with femoroacetabular hip impingement: A matched-control comparison [PDF]

, 2017
Background: Chondrolabral damage is commonly observed in patients with cam-type femoroacetabular impingement (FAI). Chondral flap reattachment has recently been proposed as a possible preservation technique.
Chahla, Jorge, Mei-Dan, Omer, Pascual-Garrido, Cecilia, Payne, Karin A, Richards, Abigail, Rodriguez-Fontan, Francisco, Uchida, Soshi   +6 more
core   +2 more sources

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Matrix-Associated Chondroplasty: A Novel Platelet-Rich Plasma and Concentrated Nucleated Bone Marrow Cell–Enhanced Cartilage Restoration Technique

Arthroscopy Techniques, 2014
Bone marrow stimulation techniques such as microfracture for the treatment of articular cartilage defects so far solely reproduce mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm.
Matthias R. Steinwachs, M.D., Bernhard Waibl, M.D., Stephanie Wopperer, M.D., Marcus Mumme, M.D.   +3 more
doaj  

The use of a novel deer antler decellularized cartilage-derived matrix scaffold for repair of osteochondral defects

Journal of Biological Engineering, 2021
Background The physiologic regenerative capacity of cartilage is severely limited. Current studies on the repair of osteochondral defects (OCDs) have mainly focused on the regeneration of cartilage tissues.
Wenhui Chu, Gaowei Hu, Lin Peng, Wei Zhang, Zhe Ma   +4 more
doaj   +1 more source

Proteoglycan production is required in initial stages of new cartilage matrix formation but inhibits integrative cartilage repair [PDF]

, 2009
The optimal stimulus to repair or regenerate cartilage is not known. We therefore modulated collagen deposition, collagen crosslinking and GAG deposition simultaneously during cartilage matrix production and integrative repair, creating more insight into
Ahsan, Aigner, Asanbaeva, Bank, Bastiaansen-Jenniskens, Bastiaansen-Jenniskens, Beekman, Billinghurst, Blunk, Bos, Bos, De Mattei, DiMicco, Farndale, Gooch, Janssen, Jenniskens, Kaul, Lafeber, Madry, Madry, Mauck, McGowan, Nelson, Tang, van de Breevaart Bravenboer, Veilleux, Verzijl, Wong   +28 more
core   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source

Meniscus-derived matrix scafolds promote the integrative repair of meniscal defects [PDF]

, 2014
Meniscal tears have a poor healing capacity, and damage to the meniscus is associated with significant pain, disability, and progressive degenerative changes in the knee joint that lead to osteoarthritis.
Ruprecht, Jacob C., Waanders, Taylor D., Rowland, Christopher R., Nishimuta, James F., Glass, Katherine A., Stencel, Jennifer, DeFrate, Louis E., Guilak, Farshid, Weinberg, J. Brice, McNulty, Amy L.   +9 more
core   +3 more sources

Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel

Arthroscopy Techniques, 2014
Bone marrow stimulation techniques for the treatment of articular cartilage defects such as microfracture so far have solely reproduced mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm ...
Matthias R. Steinwachs, M.D., Bernhard Waibl, M.D., Marcus Mumme, M.D.   +2 more
doaj  

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source