Results 71 to 80 of about 136,745 (341)

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

Defining hip cartilage repair: a modified delphi study to establish the Magnetic Resonance Evaluation of the Repair of Cartilage in the Hip (MERCH) score

Journal of Experimental Orthopaedics, 2023
Purpose To develop a standardized scoring system to evaluate pre‐ to post‐operative repair or reconstruction of hip cartilage using magnetic resonance imaging (MRI). Methods A two‐phase modified Delphi study was conducted.
The Magnetic Resonance Evaluation of the Repair of Cartilage in the Hip (MERCH) Investigators and The Canadian Hip Preservation Research Collaborative (CHIPR), Olufemi R. Ayeni   +1 more
doaj   +1 more source

Tissue engineering as a remarkable tool for cartilage repair [PDF]

, 2013
Articular cartilage is a very specialized tissue with outstanding load-bearing capacity. It consists mainly of a dense extracellular matrix (ECM) with chondrocytes embedded on it.
Neves, N. M., Reis, R. L., Silva, M. L. Alves da   +2 more
core  

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]

, 2019
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin, Silva, Eduardo A, Stilhano, Roberta S, Yamaguchi, Fabio SM   +3 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Tissue Engineering: An Alternative to Repair Cartilage

Tissue Engineering Part B: Reviews, 2019
Herein we review the state-of-the-art in tissue engineering for repair of articular cartilage. First, we describe the molecular, cellular, and histologic structure and function of endogenous cartilage, focusing on chondrocytes, collagens, extracellular matrix, and proteoglycans.
Hans L Bloem, Yaima Campos, Luis J. Cruz, Eric L. Kaijzel, Amisel Almirall, Gastón Fuentes, Gastón Fuentes   +6 more
openaire   +7 more sources

Magnetic Resonance Imaging Parameters at 1 Year Correlate With Clinical Outcomes Up to 17 Years After Autologous Chondrocyte Implantation [PDF]

, 2018
Background: The ability to predict the long-term success of surgical treatment in orthopaedics is invaluable, particularly in clinical trials. The quality of repair tissue formed 1 year after autologous chondrocyte implantation (ACI) in the knee was ...
Dugard, MN, McCall, IW, McCarthy, HS, Mennan, C, Richardson, JB, Roberts, S, Williams, JM   +6 more
core   +2 more sources

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

3D ultrasound biomicroscopy for assessment of cartilage repair tissue: volumetric characterisation and correlation to established classification systems [PDF]

European Cells & Materials, 2016
Objective and sensitive assessment of cartilage repair outcomes lacks suitable methods. This study investigated the feasibility of 3D ultrasound biomicroscopy (UBM) to quantify cartilage repair outcomes volumetrically and their correlation with ...
M Schöne, N Männicke, JS Somerson, B Marquaß, R Henkelmann, T Aigner, K Raum, RM Schulz   +7 more
doaj   +1 more source

Human stem cells and articular cartilage regeneration. [PDF]

, 2012
The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki, Iwakura, Takashi, Reddi, A Hari   +2 more
core   +4 more sources