Results 61 to 70 of about 75,319 (266)

Quantitative ultrasound biomicroscopy for the analysis of healthy and repair cartilage tissue [PDF]

European Cells & Materials, 2010
The increasing spectrum of different cartilage repair strategies requires the introduction of adequate non-destructive methods to analyse their outcome in-vivo, i.e. arthroscopically. The validity of non-destructive quantitative ultrasound biomicroscopy (
K Gelse, A Olk, S Eichhorn, B Swoboda, M Schoene, K Raum   +5 more
doaj  

Engineering Layered Magnetic Hydrogels for Cell Placement via Shear and Magnetic Field‐Induced Assembly

Advanced Materials, EarlyView.
Magnetic particles are organized into layered architectures by combining shear flow and magnetic fields, with the resulting structures governed by appropriate Mason numbers. The programmed assemblies provide spatial guidance for cell placement, linking field‐controlled self‐assembly, flow‐induced structuring and biological organization.
Guillermo Camacho, Jose R. Morillas, Jesús García‐Gutiérrez, Stefania Nardecchia, Óscar Martínez‐Cano, Juan de Vicente   +5 more
wiley   +1 more source

Current and Novel Therapeutics for Articular Cartilage Repair and Regeneration

Therapeutics and Clinical Risk Management, 2023
Bo Cong,1,2 Tao Sun,1,2 Yuchi Zhao,1,2 Mingqi Chen1 1Department of Orthopedics, Yantaishan Hospital Affiliated to Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Key Laboratory for Repair and Reconstruction of Bone & Joint,
Cong B, Sun T, Zhao Y, Chen M
doaj  

Imaging of cartilage repair procedures

Indian Journal of Radiology and Imaging, 2014
AbstractThe rationale for cartilage repair is to prevent precocious osteoarthritis in untreated focal cartilage injuries in the young and middle-aged population. The gamut of surgical techniques, normal postoperative radiological appearances, and possible complications have been described.
Darshana Sanghvi, Mihir Munshi, Dinshaw Pardiwala   +2 more
openaire   +3 more sources

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

Advanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo, Shanshan Jiang, Yimian Luo, Adele Moatti, Farnaz Matin‐Mann   +4 more
wiley   +1 more source

A Radiographic Healing Classification for Osteochondritis Dissecans of the Knee Provides Good Interobserver Reliability

Orthopaedic Journal of Sports Medicine, 2017
Background: Recent studies have examined radiographic factors associated with healing of osteochondritis dissecans (OCD) lesions of the knee. However, there is still no gold standard in determining the healing status of an OCD lesion.
David E. Ramski MD, Theodore J. Ganley MD, James L. Carey MD, MPH   +2 more
doaj   +1 more source

Advances in articular cartilage repair

Injury, 2005
Many joint and systemic disorders may lead to cartilage defects. Partial thickness defects of the articular cartilage do not have healing potential. When the lesion reaches the subchondral bone, spontaneous healing may be observed, but consists of fibrocartilaginous tissue.
Beris, A. E., Lykissas, M. G., Papageorgiou, C. D., Georgoulis, A. D.   +3 more
openaire   +3 more sources

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Engineering gene-activated bioprinted scaffolds for enhancing articular cartilage repair

Materials Today Bio
Untreated articular cartilage injuries often result in severe chronic pain and dyskinesia. Current repair strategies have limitations in effectively promoting articular cartilage repair, underscoring the need for innovative therapeutic approaches. A gene-
Min Wang, Jiachen Wang, Xin Xu, Erliang Li, Peng Xu   +4 more
doaj   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source