Results 31 to 40 of about 6,314,402 (187)

Therapeutic potential of articular cartilage regeneration using tissue engineering based on multiphase designs [PDF]

open access: yes, 2019
Articular cartilage tissue possesses poor ability to regenerate; as the lesion progresses, it extends to the underlying subchondral bone and an osteochondral (OC) defect appears complicating the therapeutic approaches.
Jorge Lara-Arias   +11 more
core   +1 more source

An overview of cartilage tissue engineering

open access: yesYonsei Medical Journal, 2000
Articular cartilage regeneration refers to the formation of new tissue that is indistinguishable from the native articular cartilage with respect to zonal organization, biochemical composition, and mechanical properties. Due to a limited capacity to repair cartilage, scar tissue frequently has a poorly organized structure and lacks the functional ...
H W, Kim, C D, Han
openaire   +3 more sources

Cartilage Tissue Engineering Using Stem Cells and Bioprinting Technology—Barriers to Clinical Translation

open access: yesFrontiers in Surgery, 2018
There is no long-term treatment strategy for young and active patients with cartilage defects. Early and effective joint preserving treatments in these patients are crucial in preventing the development of osteoarthritis. Tissue engineering over the past
Sam L. Francis   +10 more
doaj   +1 more source

Advanced Nanocomposite Hydrogels for Cartilage Tissue Engineering

open access: yesGels, 2022
Tissue engineering is becoming an effective strategy for repairing cartilage damage. Synthesized nanocomposite hydrogels mimic the structure of natural cartilage extracellular matrices (ECMs), are biocompatible, and exhibit nano–bio effects in response ...
Jianghong Huang   +6 more
doaj   +1 more source

Cartilage progenitor cells combined with PHBV in cartilage tissue engineering

open access: yesJournal of Translational Medicine, 2019
Background Bone marrow-derived stem cells (BMSCs) and chondrocytes have been reported to present “dedifferentiation” and “phenotypic loss” during the chondrogenic differentiation process in cartilage tissue engineering, and cartilage progenitor cells ...
Ke Xue   +5 more
doaj   +1 more source

Progress and prospect of technical and regulatory challenges on tissue-engineered cartilage as therapeutic combination product

open access: yesBioactive Materials, 2023
Hyaline cartilage plays a critical role in maintaining joint function and pain. However, the lack of blood supply, nerves, and lymphatic vessels greatly limited the self-repair and regeneration of damaged cartilage, giving rise to various tricky issues ...
Xiaolei Guo   +7 more
doaj   +1 more source

CARTILAGE TISSUE ENGINEERING [PDF]

open access: yesBiomedical Engineering: Applications, Basis and Communications, 2005
Tissue engineering is a new approach for articular cartilage repair. The aim of the present article was to review the current status of cartilage tissue engineering researches. The scaffold materials used for cartilage tissue engineering, the in vitro, in vivo studies and the clinical trials were all reviewed.
CHIH-HUNG CHANG   +3 more
openaire   +1 more source

Bioreactor based engineering of large-scale human cartilage grafts for joint resurfacing [PDF]

open access: yes, 2010
Apart from partial or total joint replacement, no surgical procedure is currently available to treat large and deep cartilage defects associated with advanced diseases such as osteoarthritis.
Dieter Wirz   +15 more
core   +1 more source

Tissue engineering strategies hold promise for the repair of articular cartilage injury

open access: yesBioMedical Engineering OnLine
Articular cartilage damage and wear can result in cartilage degeneration, ultimately culminating in osteoarthritis. Current surgical interventions offer limited capacity for cartilage tissue regeneration and offer only temporary alleviation of symptoms ...
Chenhui Yang   +6 more
doaj   +1 more source

Precultivation of engineered human nasal cartilage enhances the mechanical properties relevant for use in facial reconstructive surgery [PDF]

open access: yes, 2006
To investigate if precultivation of human engineered nasal cartilage grafts of clinically relevant size would increase the suture retention strength at implantation and the tensile and bending stiffness 2 weeks after implantation.
Pierer, Gerhard   +21 more
core   +1 more source

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