Results 71 to 80 of about 6,314,402 (187)

Utilizing micropellets as building blocks in cartilage tissue engineering [PDF]

open access: yes, 2015
Osteoarthritis is the most common cause of pain and disability in Australia. This project describes a method where hundreds of cartilage microtissues are generated as tiny building blocks for assembly into larger tissues suitable for cartilage defect ...
Babur, Betul
core  

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

open access: yes, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Candrian, Christian   +9 more
core   +2 more sources

Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration

open access: yesBioMedical Engineering OnLine
Articular cartilage injury is a serious bone disease that can result in disabilities. With the rapid increase in the aging population, this disorder has become an increasingly important public health issue.
Chun-Sheng Li   +8 more
doaj   +1 more source

Regulation of lubricin for functional cartilage tissue regeneration: a review

open access: yesBiomaterials Research, 2018
Background Lubricin is chondrocyte-secreted glycoprotein that primarily conducts boundary lubrication between joint surfaces. Besides its cytoprotective function and extracellular matrix (ECM) attachment, lubricin is recommended as a novel biotherapeutic
Yunsup Lee   +2 more
doaj   +1 more source

Environments for zonal cartilage tissue engineering [PDF]

open access: yes, 2015
Articular cartilage is a highly organized tissue with cellular and matrix properties that vary with depth zones. Regenerating this zonal organization has proven difficult in tissue-engineered cartilage to treat damaged cartilage.
Kuaha, Kunnika
core  

Evaluation of Articular Cartilage Repair Using Biodegradable Nanofibrous Scaffolds in a Swine Model: A Pilot Study

open access: yes, 2011
The aim of this study was to evaluate a cell-seeded nanofibrous scaffold for cartilage repair in vivo. We used a biodegradable poly(e-caprolactone) (PCL) nanofibrous scaffold seeded with allogeneic chondrocytes or xenogeneic human mesenchymal stem cells (
江鴻生;郭宗甫;李宣書;段崇智;江清泉   +1 more
core   +1 more source

Biomechanical assessment of extracellular matrix in native and tissue engineered cartilage across lenght scales [PDF]

open access: yes, 2012
Musculoskeletal diseases (MSD) and related disorders account for the largest fraction of temporary and permanent disabilities, and are often considered to be an inevitable consequence of aging.
Loparic, Marko
core   +1 more source

Principles of cartilage tissue engineering in TMJ reconstruction

open access: yesHead & Face Medicine, 2008
Diseases and defects of the temporomandibular joint (TMJ), compromising the cartilaginous layer of the condyle, impose a significant treatment challenge. Different regeneration approaches, especially surgical interventions at the TMJ's cartilage surface,
Hohoff Ariane   +6 more
doaj   +1 more source

A low percentage of autologous serum can replace bovine serum to engineer human nasal cartilage [PDF]

open access: yes, 2008
For the generation of cell-based therapeutic products, it would be preferable to avoid the use of animal-derived components. Our study thus aimed at investigating the possibility to replace foetal bovine serum (FBS) with autologous serum (AS) for the ...
Farhadi, J.   +11 more
core   +1 more source

Cartilage tissue engineering

open access: yes, 2023
Focal articular cartilage defects occur often during knee trauma. Articular cartilage has a limited repair capacity, so it is necessary to repair these cartilage defects to prevent further degeneration of the knee joint. Mesenchymal progenitor cells, often referred to as mesenchymal stem or stromal cells (MSCs) are promising cells for cartilage tissue ...
openaire   +3 more sources

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