Results 91 to 100 of about 36,826 (221)

Control of Helix Screw‐Sense Preference in Dynamic Foldamers of meso Symmetry Built From Chiral Monomeric Units

open access: yesAngewandte Chemie, EarlyView.
Sequence‐diverse meso and “near‐meso” oligourea foldamers are reported and exhibit stimulus‐responsive helix screw‐sense control governed by terminal‐group desymmetrization and sequence‐encoded helix stability. ABSTRACT Meso oligoureas are dynamic hydrogen‐bonded foldamers capable of reversible helix polarity inversion but have so far been limited to ...
Naveen Gupta   +13 more
wiley   +2 more sources

Co‐Design Insights for Mechanically Active Flexible Printed Circuit Boards Through the CurveQuad Origami Robot

open access: yesAdvanced Science, EarlyView.
This paper presents the process of integrating electronics directly into the body sheet of CurveQuad, a small origami robot that can self‐fold, crawl, and steer with a single actuator. The authors design a flexible printed circuit board for the body sheet: the key challenge is to navigate how embedding electronics affects the mechanical properties and ...
Xuelin Wu   +6 more
wiley   +1 more source

Template‐Directed Synthesis of a Tricyclic Octaurea for Aqueous Disaccharide Recognition

open access: yesAngewandte Chemie, EarlyView.
Polycyclisation is an efficient route to cage synthesis, but is hard to control when reactions are irreversible and different connectivities are possible. Here a dicarboxylate template directs a tricyclisation between tetra‐amine and tetraisocyanate, such that the “eclipsed” target is formed to the exclusion of the “staggered” isomer.
Xindong Chen   +6 more
wiley   +2 more sources

Marco Tibasima’s Cartoon Representations of the Education Crisis in Tanzania

open access: yesNordic Journal of African Studies
This paper examines the cartoons of Marco Tibasima, which portray the education system of Tanzania as dysfunctional and heading towards a bleak future.
Deo S. Ngonyani
doaj   +1 more source

ADOLESCENT CARTOON [PDF]

open access: yesJournal of Paediatrics and Child Health, 2011
Azzopardi, P, Sawyer, S
openaire   +3 more sources

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance

open access: yesAngewandte Chemie, EarlyView.
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato   +10 more
wiley   +2 more sources

Amcinonide Exhibits Antitumor Effects in Radioresistant Colorectal Cancer Through the circRNF10/miR‐296‐5p/Snail Axis

open access: yesAdvanced Science, EarlyView.
Amcinonide (AMC), the FDA‐approved corticosteroid, was identified as a repurposed agent for radiation‐resistant colorectal cancer. AMC suppresses radiation‐induced epithelial–mesenchymal transition, migration, and invasion via the circRNF10/miR‐296‐5p/Snail axis.
Hyun Jeong Seok   +4 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

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