Results 81 to 90 of about 169,180 (287)

Mocking a Perilous Prediction: Currier and Ives’ Political Cartoons

open access: yes, 2014
Currier and Ives’ political cartoons, while comical, also represent the general undertones of the time as well as people’s feelings regarding this era of political controversy.
Sutter, Megan A.
core  

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

open access: yesAdvanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu   +7 more
wiley   +1 more source

THE USE OF CARTOONS IN POPULAR PROTESTS THAT FOCUS ON GEOGRAPHIC, SOCIAL, ECONOMIC AND POLITICAL ISSUES

open access: yesEuropean Journal of Geography, 2013
The comics and related arts (cartoons, graffiti, illustrated posters and signs) have always played an important role in shaping public protests. From the French Revolution to the recent Arab Spring revolutionary wave of demonstrations and protests ...
Mary TOTRY, Arnon MEDZINI
doaj   +2 more sources

“Silence is the best answer for a bully”: an exploration of humour techniques in selected Nigerian newspaper political cartoons

open access: yesLanguage and Semiotic Studies
Newspaper political cartoons, known for their satirical nature, employ semiotic and linguistic techniques to comment on or criticise political leaders and events humorously.
Osisanwo Ayo, Atoloye Lekan
doaj   +1 more source

A Hermeneutical Study of Mass Media Cartoons in The Political Year of 2024

open access: yesNirmana
Mass media cartoons are works of visual communication that have the 'task' of conveying opinions or criticism of socio-political discourse with a touch of humor.
I Wayan Nuriarta   +1 more
doaj   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

Ice Cream [PDF]

open access: yes, 2018
Ice Cream is a series of 2D and 3D depictions of lawn ornaments, Charlie Brown, and novelty ice cream bars, which question how White America is indoctrinated through seemingly innocuous images and objects.
Peterson, Richard Frank
core   +2 more sources

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Iconographie professionnelle et féminisation du travail policier à New York (1945-1980)

open access: yesImages du Travail, Travail des Images, 2019
Can images of an institutional magazine be used as visual archives of women’s police work ? Through the study of Spring 3100, the magazine of the New York Police Department, and a comparison with the work of photographer Jane Hoffer, this article ...
Yann Philippe
doaj   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

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