Results 51 to 60 of about 45,815 (295)

Impartial humor in war times

open access: yesThe European Journal of Humour Research
This article examines the use of impartial humour in political cartoons on the Russian-Ukrainian war. The dataset includes 18 political cartoons from Australia, the USA, Algeria, Morocco, Argentina, Brazil, Italy, Greece, Taiwan, Qatar, Iran, Ukraine ...
Orest Semotiuk, Yana Hladyr
doaj   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

Enhancing South African science education: The impact of concept cartoons on teaching terminology during science investigations in intermediate phase

open access: yesReading & Writing
Background: The study explored how concept cartoons can be used as a teaching tool to improve Grade 4 learners’ understanding of scientific terminology.
Warda Abrahams
doaj   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

The role of cartoons in portraying the reality: political cartoons based on “october 26th political crisis” [PDF]

open access: yes, 2021
Mass media influence the people and the political situation of the country. According to that Political cartoons are an important part of any newspaper. Newspapers involve the influence of knowledge of people and the channel comparatively making more
Linganathan, Anutharsi
core  

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

Cartoons and economics: general analysis based on colombian economic cartoons. [PDF]

open access: yes
May cartoons be considered as a viable and credible source for the study of economics? There is hardly any research on the subject, even though there is a quite significant amount of cartoons with economic content.
Villaveces Niño, Juanita   +1 more
core  

Digital cartoons : collaborative activism in Hong Kong

open access: yes, 2023
This chapter analyses some new ways of digital cartoon production that have been adopted in social movements in Hong Kong over the past few years. Two tendencies can be seen in the production of such cartoons: the first one is there are more citizen ...
Chu, Kin Wai
core   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

open access: yesAdvanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang   +15 more
wiley   +1 more source

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