Results 261 to 270 of about 267,421 (305)

Genome editing and regeneration pipeline for engineering disease resistance in tomato using CRISPR/Cas9. [PDF]

Front Plant Sci
Erdoğan İ, Debbarma R, Sherry M, Mancak İ, Grant M, Tör M.   +5 more
europepmc   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

CasMiner: a deep-learning tool for high-throughput mining and rational design of efficient Cas9. [PDF]

Natl Sci Rev
Xu G, Li S, Li H, Ren X, Ding Y, Pang X, Liu X, Tang Q, Tu T, Wang Y, Luo H, Yao B, Tian J, Chen R, Guan F.   +14 more
europepmc   +1 more source

Editing <i>Candida</i>: Origins and Advances of CRISPR Tools. [PDF]

Biomolecules
Schulze A, Kainz K, Bauer MA, Carmona-Gutierrez D.   +3 more
europepmc   +1 more source

CRISPR-Cas9-based gene editing as a proof-of-concept approach in an inborn error of immunity caused by a DCLRE1C variant. [PDF]

Immunol Res
Duran T, Karaselek MA, Dagdelen B, Kuccukturk S, Guner SN, Keles S, Reisli I.   +6 more
europepmc   +1 more source

CRISPR/Cas Genome Editing and Its Applications in Cereal Crop Improvement. [PDF]

Plant Environ Interact
Kaniganti S, Saini H, Chaitanya AK, Hegde N, Shah P, Magar ND, Rijal R, Kaushik JJ, Nanda D, Sachan S, Kumar A, Bhoite R, Jamedar HR.   +12 more
europepmc   +1 more source