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CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein

Molecular Genetics and Genomics, 2017
Previous works using human tripronuclear zygotes suggested that the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system could be a tool in correcting disease-causing mutations. However, whether this system was applicable in normal human (dual pronuclear, 2PN) zygotes was unclear.
Lichun Tang   +10 more
openaire   +2 more sources

CRISPR/Cas9-NHEJ

ACM SIGGRAPH 2018 Posters, 2018
CRISPR/Cas9-NHEJ: Action in the Nucleus (2017) is derived from an interdisciplinary creative process. This paper discusses the creation of this 210° scientific visualization, the usage of data from the worldwide Protein Data Bank, and the audio-visual presentation in an interactive dome setup.
Martina R. Fröschl, Alfred Vendl
openaire   +1 more source

CRISPR/Cas9

2022
Sylvia Uzochukwu, Arinze S. Okoli
openaire   +1 more source

CRIPSR-Cas9

médecine/sciences, 2023
openaire   +1 more source

Applying CRISPR–Cas9 tools to identify and characterize transcriptional enhancers

Nature Reviews Molecular Cell Biology, 2016
Rui Lopes, Gozde Korkmaz, Reuven Agami
exaly  

High-throughput functional genomics using CRISPR–Cas9

Nature Reviews Genetics, 2015
Ophir Shalem   +2 more
exaly  

Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases

Nature Reviews Genetics, 2016
Shengdar Q Tsai, J Keith Joung
exaly  

Inhibition of CRISPR-Cas9 with Bacteriophage Proteins

Cell, 2017
Melanie R Silvis   +2 more
exaly  

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

Nature Biotechnology, 2020
Jordan L Doman   +2 more
exaly  

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