Results 71 to 80 of about 1,452,828 (281)

Factors influencing young people’s transitions from child to adult mental health services in Wales

open access: yesInternational Journal of Population Data Science
Objectives This presentation provides an overview of young peoples’ transitions from child to adult mental health services in Wales. Transitions are unstable times where need for support can be greatest, yet many young adults fail to qualify for ongoing 
Louisa Roberts   +3 more
doaj   +1 more source

Prevalence of polypharmacy: Comparing the status of Indian states

open access: yesIndian Journal of Community and Family Medicine, 2019
Introduction: The word “poly” is Greek and means many or much. However, the term polypharmacy has been given definitions connected both to the use of more than a certain number of drugs concomitantly and to the clinical appropriateness of drug use ...
Priya Sharma, N L Gupta, H S Chauhan
doaj   +1 more source

Intranuclear cascade models lack dynamic flow [PDF]

open access: yes, 2006
We study the recent claim that the intranuclear cascade model exhibits collective sidewards flow. 4000 intranuclear cascade simulations of the reaction Nb(400 MeV/nucleon)+Nb are performed employing bound and unbound versions of the Cugnon cascade.
Cugnon, Joseph   +4 more
core  

Learning Complexity-Aware Cascades for Deep Pedestrian Detection

open access: yes, 2015
The design of complexity-aware cascaded detectors, combining features of very different complexities, is considered. A new cascade design procedure is introduced, by formulating cascade learning as the Lagrangian optimization of a risk that accounts for ...
Cai, Zhaowei   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Global polycrisis: the causal mechanisms of crisis entanglement

open access: yesGlobal Sustainability
Multiple global crises – including the pandemic, climate change, and Russia's war on Ukraine – have recently linked together in ways that are significant in scope, devastating in effect, but poorly understood.
Michael Lawrence   +5 more
doaj   +1 more source

Electromagnetic Cascade in the Early Universe and its Application to the Big-Bang Nucleosynthesis

open access: yes, 1994
We investigate the electromagnetic cascade initiated by injection of very high energy photons in the early Universe and calculate the cascade spectrum by solving a set of Boltzmann equations numerically.
Kawasaki, M., Moroi, T.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Heteroatom self-doped graphitic carbon materials from Sargassum thunbergii with improved supercapacitance performance

open access: yesAdvanced Sensor and Energy Materials
It is well-known that high specific surface area and improved pore structure is significantly desired for the application of supercapacitor based on biomass-based activated carbon. Herein, Sargassum thunbergii was selected as carbon precursor.
Hui Xu   +6 more
doaj   +1 more source

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