Results 61 to 70 of about 297,562 (257)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Macroscopic nucleon-nucleon correlations caused by the bounce-off process in energetic collisions of heavy nuclei [PDF]

, 2006
Two-particle correlation data are presented for the reaction Ar (800 MeV/ nucleon) + Pb. The experimental results are analyzed in the nuclear fluid dynamical and in a linear cascade model.
Csernai, László Pal, Greiner, Walter, Knoll, Jörn, Nagamiya, Shoji, Stöcker, Horst, Tanihata, Isao   +5 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction

Molecules
3,4-bridged indoles are underrepresented among the vast number of indoles described in the literature. Attempts to access 3,4-macrocyclized indoles led to the unexpected formation of a novel tetracyclic indole through intramolecular acid-catalyzed ring ...
Felix Potlitz, Gottfried J. Palm, Anja Bodtke, Michael Lammers, Dennis Schade, Andreas Link   +5 more
doaj   +1 more source

A Novel Strategy for Biomass Upgrade: Cascade Approach to the Synthesis of Useful Compounds via C-C Bond Formation Using Biomass-Derived Sugars as Carbon Nucleophiles

Molecules, 2016
Due to the depletion of fossil fuels, biomass-derived sugars have attracted increasing attention in recent years as an alternative carbon source. Although significant advances have been reported in the development of catalysts for the conversion of ...
Sho Yamaguchi, Toshihide Baba
doaj   +1 more source

K^+ momentum spectrum from (K^-,K^+) reactions in intranuclear cascade model

, 1996
In a framework of intranuclear cascade (INC) type calculation, we study a momentum spectrum in reactions \KK at a beam momentum of 1.65 GeV/c. INC model calculations are compared with the relativistic impulse approximation (RIA) calculations to perform ...
A Engel, A Ohnishi, Aichelin, Aichelin, Aoki, Behrend, Berenguer, Berge, Bertsch, Bertsch, Bohnet, Brown, Cassing, Cassing, Chen, Cugnon, Cugnon, Cugnon, Cugnon, Danyz, Dauber, DeJager, Dover, Frankel, Ginocchio, Ginocchio, Gobbi, Horiuchi, Horowitz, Iijima, Ko, Kruse, Li, Li, Maruyama, Maruyama, Maruyama, Maruyama, Maruyama, Molitoris, Molitoris, Molitoris, Mosel, Nara, Niita, Ono, Ono, Ono, Ono, Peilert, Prowse, Salcedo, Sano, Sorge, Sorge, Söcker, T Harada, Vicente-Vacas, Y Nara, Yariv   +59 more
core   +1 more source

Extended Hauser-Feshbach Method for Statistical Binary-Decay of Light-Mass Systems [PDF]

, 1997
An Extended Hauser-Feshbach Method (EHFM) is developed for light heavy-ion fusion reactions in order to provide a detailed analysis of all the possible decay channels by including explicitly the fusion-fission phase-space in the description of the ...
A. Bohr, A. Gavron, A. H. Wapstra, A. Ray, A. V. Ignatyuk, B. Fornal, B. Shivakumar, C. Beck, C. Beck, C. Beck, C. Beck, C. Beck, C. Beck, C. Beck, C. Beck, D. Durand, D. Mahboub, D. R. Chakrabarty, F. Ajzenberg-Selove, F. Auger, F. Pühlhofer, H. J. Krappe, J. Gomez del Campo, J. Gomez del Campo, J. Gomez del Campo, J. M. Oliveira, Jr., J. R. Huizenga, J. R. Natowitz, K. A. Farrar, K. Yuasa-Nakagawa, L. G. Moretto, L. G. Sobotka, N. Van Sen, O. D. Grudzevich, P. M. Endt, R. G. Charity, R. G. Stokstad, R. K. Gupta, R. Nouicer, R. Nouicer, S. J. Sanders, S. J. Sanders, S. J. Sanders, S. J. Sanders, S. M. Lee, S. Shlomo, T. Matsuse, T. Matsuse, T. Matsuse, W. Hauser, W. Yokota, Y. Futami, Y. H. Pu   +52 more
core   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

One-Pot Anodic Electrodeposition of Dual-Cation-Crosslinked Sodium Alginate/Carboxymethyl Chitosan Interpenetrating Hydrogel with Vessel-Mimetic Heterostructures

Journal of Functional Biomaterials
This study develops a one-pot anodic templating electrodeposition strategy using dual-cation-crosslinking and interpenetrating networks, coupled with pulsed electrical signals, to fabricate a vessel-mimetic multilayered tubular hydrogel.
Xuli Li, Yuqing Qu, Yong Zhang, Pei Chen, Siyu Ding, Miaomiao Nie, Kun Yan, Shefeng Li   +7 more
doaj   +1 more source

Integral measurement of the 12C(n, p)12B reaction up to 10 GeV [PDF]

, 2016
The integral measurement of the 12C(n, p)12B reaction was performed at the neutron time-offlight facility n TOF at CERN. The total number of 12B nuclei produced per neutron pulse of the n TOF beam was determined using the activation technique in ...
Altstadt, Sebastian G., Bosnar, D., Colonna, Nicola, Cortés Giraldo, Miguel Antonio, Mengoni, A., Praena Rodríguez, Javier, Quesada Molina, José Manuel, Ventura, A., Zugec, P.   +8 more
core   +1 more source