Research on Key Technologies of Personalized Intervention for Chronic Diseases Based on Case-Based Reasoning. [PDF]
Comput Math Methods Med, 2021 Zhang L, Qi P.
europepmc +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Fault Detection in the MSW Incineration Process Using Stochastic Configuration Networks and Case-Based Reasoning. [PDF]
Sensors (Basel), 2021 Ding C, Yan A.
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Integrating functional data analysis with case-based reasoning for hypertension prognosis and diagnosis based on real-world electronic health records. [PDF]
BMC Med Inform Decis Mak, 2022 Qi P, Wang F, Huang Y, Yang X.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Combining Axiomatic Design and Case-Based Reasoning in a Design Methodology of Mechatronics Products [PDF]
, 2009 Organised by: Cranfield UniversityCurrent market environments are volatile and unpredictable. The ability for design products to meet customer’s requirements has become critical to success.
Janthong, N., Brissaud, D., Butdee, S.
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Fuzzy case-based reasoning approach for finding COVID-19 patients priority in hospitals at source shortage period. [PDF]
Expert Syst Appl, 2021 Geetha S +3 more
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