Results 131 to 140 of about 43,177 (231)

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

CSNK1D inhibition suppresses head and neck squamous cell carcinoma progression through SHH and PTCH1 pathway

Cell Death and Disease
Casein kinase 1δ (CK1δ, encoded by casein kinase 1 delta) (CSNK1D) is a serine/threonine protein kinase closely associated with cancer development.
Li Yang, Xiang Li, Yun Zhu, Yu Zhang, Zheqi Liu, Chengzhong Lin, Canhua Jiang, Yu-Xiong Su, Tong Ji, Yang Wang, Jun Gao, Jinhai Ye   +11 more
doaj   +1 more source

Effect of Nutritional Factors on Mental Health Problems in Autism Spectrum Disorder: A Narrative Synthesis of Current Evidence

Brain and Behavior, Volume 16, Issue 7, July 2026.
This narrative synthesis of 21 studies evaluates nutritional interventions for psychiatric comorbidities in ASD. Vitamin D3, omega‐3 fatty acids, and probiotics show preliminary benefits for anxiety and irritability, whereas GFCF diet results remain inconclusive.
Nalan Hakime Nogay, Gulin Ozturk Ozkan
wiley   +1 more source

Antibiofilm, Antimicrobial, and Anti‐inflammatory Potential of Rubus chamaemorus Rhizome, Leaf, and Fruit Extracts

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Rhizome, leaf, and fruit extracts of cloudberry (Rubus chamaemorus L., Rosaceae) are systematically evaluated for biological activities relevant to wound infections. The methanolic leaf extract exhibits potent antibiofilm and anti‐inflammatory activity without cytotoxicity, whereas rhizome and fruit extracts are largely inactive.
Hildegard Kieninger, Stefanie Koenig, Nadin Schultze, Ulrike Garscha, Sebastian Guenther, Christian Schulze   +5 more
wiley   +1 more source

Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation.

, 2020
Hippo signalling integrates diverse stimuli related to epithelial architecture to regulate tissue growth and cell fate decisions. The Hippo kinase cascade represses the growth-promoting transcription co-activator Yorkie.
David Frith (7584005), Maxine V Holder (8319039), Ambrosius P Snijders (8119406), Alexander D Fulford (8319036), Paulo S Ribeiro (8319042), Nicolas Tapon (270959)   +5 more
core  

Integration of Three‐Dimensional Cell Culture Techniques and Photobiomodulation for Supportive Differentiation of Adipose‐Derived Stem Cells into Smooth Muscle

Cell Biochemistry and Function, Volume 44, Issue 7, July 2026.
ABSTRACT Photobiomodulation (PBM) has gained recognition as a promising, non‐invasive strategy to enhance the differentiation of adipose‐derived stem cells (ADSCs) into smooth muscle cells (SMCs), particularly when used together with a three‐dimensional (3D) hydrogel culture system.
Christevie Mbuyu, Heidi Abrahamse, Anine Crous   +2 more
wiley   +1 more source

Deletion of Cdc28 cyclin (HGC1) and casein kinase 1 (YCK2) disrupt normal hyphal growth.

, 2021
(A) Deletion of Cdc28 cyclin (HGC1) and casein kinase 1 (YCK2) disrupt normal hyphal growth in WT and PR13 backgrounds. (B) The plot shows the percent of filamentous cells in YPD medium at 30°C (-control) and after 2-h growth in GlcNAc medium at 37°C ...
Thomas F. Jannace (11278826), Haoyu Si (386609), Krishna R. Veeramah (11278829), John D. Haley (8129934), Kyunghun Min (162508), James B. Konopka (460667)   +5 more
core   +1 more source

Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer

Cell Reports, 2017
Summary: The serine/threonine protein phosphatase 5 (PP5) regulates multiple cellular signaling networks. A number of cellular factors, including heat shock protein 90 (Hsp90), promote the activation of PP5.
Natela Dushukyan, Diana M. Dunn, Rebecca A. Sager, Mark R. Woodford, David R. Loiselle, Michael Daneshvar, Alexander J. Baker-Williams, John D. Chisholm, Andrew W. Truman, Cara K. Vaughan, Timothy A. Haystead, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour   +13 more
doaj   +1 more source

Remodelling the tumour microenvironment and beyond: ERO1A as a multifaceted regulator and emerging therapeutic target in cancer

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
ERO1A exhibits oncogenic functions, including promoting tumour progression, metastasis, epithelial‒mesenchymal transition, angiogenesis, immune evasion and metabolic reprogramming. ERO1A is also identified as a diagnostic biomarker and a factor contributing to therapy resistance (chemotherapy and immunotherapy).
Jing Mao, Kai Wang
wiley   +1 more source

Recent advances in pancreatic β‐cell dysfunction in type 2 diabetes mellitus: Intracellular stress and dedifferentiation

Journal of Diabetes Investigation, EarlyView.
Nozomi Kido, Shun‐ichiro Asahara
wiley   +1 more source