Results 151 to 160 of about 43,177 (231)
From Synapses to Circuits, the Role of KIBRA and the WWC Family in Adaptive Brain Function
Journal of Neurochemistry, Volume 170, Issue 7, July 2026.KIBRA (WWC1) has been the subject of scientific interest since its initial association with nonpathological variation in human memory performance. This review discusses subsequent work in animal models demonstrating that KIBRA supports memory function.
Lenora J. Volk
wiley +1 more source
Liver International, Volume 46, Issue 7, July 2026.ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley +1 more source
Neurobiology of DiseaseHyperphosphorylated TAR DNA-binding protein 43 (TDP-43) aggregates in the cytoplasm of neurons is the neuropathological hallmark of amyotrophic lateral sclerosis (ALS) and a group of neurodegenerative diseases collectively referred to as TDP-43 ...
Vivian I. Ko +4 more
doaj +1 more source
Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2. [PDF]
EMBO Mol Med, 2023 Torii S +11 more
europepmc +1 more source
Molecular Plant Pathology, Volume 27, Issue 7, July 2026.The core RXLR effector Pi05910 of P. infestans suppresses host immunity and growth by promoting destabilisation of its binding protein RACK1 via the 26S proteasome pathway, leading to the suppression of PTI and protein translation. ABSTRACT Late blight, caused by oomycete pathogen Phytophthora infestans, is one of the most devastating diseases of ...
Xiong Liu +7 more
wiley +1 more source
Rapid CO2 effects on protein‐related metabolism during photosynthetic gas exchange
The Plant Journal, Volume 127, Issue 1, July 2026.SUMMARY It is common practice to vary atmospheric CO2 mole fraction (Ca) during gas exchange experiments to manipulate photorespiration and explore photosynthetic properties such as maximum carboxylation velocity. In doing so, it is assumed that changing Ca essentially alters the carboxylation‐to‐oxygenation ratio, with negligible effects on other ...
Corentin Dourmap +5 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.A modular Rh‐catalyzed synthetic approach enabled the preparation of diverse reactive fragments from available substrates. The reactive fragments modified Aurora A kinase via several distinct modification reaction classes. In a complex biological environment, the constellation of modified proteins depended critically on the reactive fragment structure.
Julian Chesti +8 more
wiley +1 more source
openLa lotta contro la malaria ha attraversato secoli di progressi scientifici, dalla sua prima descrizione nei testi di Ippocrate fino alle moderne terapie antimalariche e ai recenti sviluppi nel campo dei vaccini.
BROCCHETTI, ANNA
core
A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases
ChemBioChem, Volume 27, Issue 11, 15 June 2026.Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley +1 more source
CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions
Cell Death and DiseaseThe aberrant upregulation of Yes-associated protein 1 (YAP1) in a variety of solid cancers contributes to tumor progression and poor clinical outcomes, rendering it an appealing therapeutic target.
Lei Huang +12 more
doaj +1 more source