Results 111 to 120 of about 43,522 (228)

Integration of Three‐Dimensional Cell Culture Techniques and Photobiomodulation for Supportive Differentiation of Adipose‐Derived Stem Cells into Smooth Muscle

Cell Biochemistry and Function, Volume 44, Issue 7, July 2026.
ABSTRACT Photobiomodulation (PBM) has gained recognition as a promising, non‐invasive strategy to enhance the differentiation of adipose‐derived stem cells (ADSCs) into smooth muscle cells (SMCs), particularly when used together with a three‐dimensional (3D) hydrogel culture system.
Christevie Mbuyu, Heidi Abrahamse, Anine Crous   +2 more
wiley   +1 more source

ELF5 modulates casein synthesis in goat mammary epithelial cells via JAK2/STAT5 signaling pathway [PDF]

Animal Bioscience
Objective Goat milk contains a high concentration of caseins which are beneficial to human health. Understanding the regulatory mechanisms of casein synthesis in goats contribute to improving milk quality.
Yuzhu Guo, Cunxia Ma, Tianxiang Meng, Tongtong Tu, Shuangshuang Cui, Yinghui Ling, Yunhai Zhang, Hongyu Liu, Ning Song   +8 more
doaj   +1 more source

Remodelling the tumour microenvironment and beyond: ERO1A as a multifaceted regulator and emerging therapeutic target in cancer

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
ERO1A exhibits oncogenic functions, including promoting tumour progression, metastasis, epithelial‒mesenchymal transition, angiogenesis, immune evasion and metabolic reprogramming. ERO1A is also identified as a diagnostic biomarker and a factor contributing to therapy resistance (chemotherapy and immunotherapy).
Jing Mao, Kai Wang
wiley   +1 more source

Casein kinase 2 phosphorylates recombinant human spermidine/spermine N1-acetyltransferase on both serine and threonine residues [PDF]

, 1996
Casein kinase 2 purified from human erythrocyte cytosol has been found to phosphorylate human spermidine/spermine N1-acetyltransferase (SSAT) expressed as a fusion protein in E.
CLARI, GIULIO, C. VARGIU, G. TESTORE, M. A. GRILLO, S. COLOMBATTO, Grillo, Maria Angelica, Colombatto, Sebastiano, BORDIN, LUCIANA, TONINELLO, ANTONIO   +8 more
core   +1 more source

Phosphorylation of maize RAB-17 protein by casein kinase 2.

Journal of Biological Chemistry, 1991
The maize gene RAB-17, which is responsive to abscisic acid, encodes a basic glycine-rich protein containing, in the middle part of its sequence, a cluster of 8 serine residues followed by a putative casein kinase 2-type substrate consensus sequence. This protein was found to be highly phosphorylated in vivo. Here, we show that RAB-17 protein is a real
Plana, M., Itarte, E., Eritja Casadellà, Ramón, Goday, Adela, Pagès, Montserrat, Martínez Rodríguez, María del Carmen   +5 more
openaire   +3 more sources

Recent advances in pancreatic β‐cell dysfunction in type 2 diabetes mellitus: Intracellular stress and dedifferentiation

Journal of Diabetes Investigation, EarlyView.
Nozomi Kido, Shun‐ichiro Asahara
wiley   +1 more source

Osimertinib Resistance in EGFR‐Mutated Non–Small Cell Lung Cancer: Mechanisms and Therapeutic Strategies

MedComm, Volume 7, Issue 7, July 2026.
This review illustrates the key mechanisms of osimertinib resistance in EGFR‑mutant NSCLC, including EGFR‑dependent mutations, bypass pathway activation, and SMARCA4‑mediated epigenetic regulation. We also summarize emerging targeted therapies and future perspectives to overcome EGFR‑TKI resistance.
Junfeng Guo, Qiuyuan Wen, Songqing Fan
wiley   +1 more source

Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications

ChemistryOpen, Volume 15, Issue 7, July 2026.
Magnetic bead engineering for liquid biopsy diagnostics reviews advances in magnetic bead design for the selective enrichment of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and extracellular vesicles (EVs) from complex biofluids.
Beatriz Naranjo‐Martínez, Ana Laura Coria‐Gutiérrez, Sunčica Sukur, Sedef Ozel‐Okcu, Václav Ranc, Francisco J. Terán, Franca Raucci, Marco A. Pierotti, Domenico Scionti, Anna Piperno   +9 more
wiley   +1 more source

Impact of protein kinase CK2 downregulation and inhibition on oncomir clusters 17 ~ 92 and 106b ~ 25 in prostate, breast, and head and neck cancers

Molecular Medicine
Background Protein kinase CK2 is a ubiquitous and highly conserved protein Ser/Thr kinase with diverse cell functions. CK2 is upregulated in various cancers and affects numerous aspects of their underlying pathobiology.
Betsy T. Kren, Christine M. Henzler, Khalil Ahmed, Janeen H. Trembley   +3 more
doaj   +1 more source

CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ

Nature Communications, 2019
In atherosclerotic plaques, transformation of macrophages into foam cells is a key step in initiating the inflammatory response. Here Fan et al. show that casein kinase 2-interacting protein-1 (CKIP-1) limits foam cell formation and atherosclerosis by ...
Jiao Fan, Lifeng Liu, Qingyan Liu, Yu Cui, Binwei Yao, Minghua Zhang, Yabing Gao, Yesheng Fu, Hongmiao Dai, Jingkun Pan, Ya Qiu, Cui Hua Liu, Fuchu He, Yu Wang, Lingqiang Zhang   +14 more
doaj   +1 more source