Results 141 to 150 of about 34,988 (231)

Phosphorylation of the p53 tumour-suppressor protein at three N-terminal sites by a novel casein kinase I-like enzyme

, 1992
Wild-type mouse p53, expressed in Escherichia coli, was phosphorylated by highly purified casein kinase I (CKI) from rabbit muscle. The major site of phosphorylation in the p53 was identified as serine 6, which is known to be phosphorylated in vivo ...
Campbell, D. G., Palmer, R. H., Meek, D. W., Milne, D. M.   +3 more
core  

Molecular and biochemical characterisation of human casein kinase I alpha splice variants

, 1998
Casein kinase I (CKI), one of the first protein kinases identified biochemically, is a serine/ threonine protein kinase known to exist in multiple isoforms in mammals.
Yong, Thomas Joon Kin.
core   +1 more source

Phase I first-in-human dose escalation study of the oral casein kinase 1α and cyclin dependent kinase 7/9 inhibitor BTX A51 in advanced MDS and AML

Journal of Hematology & Oncology
Background BTX A51, a first-in-class oral small molecule inhibitor of casein kinase 1α (CK1α) and cyclin-dependent kinase (CDK) 7 and 9, induces apoptosis of leukemic cells by activating p53 and inhibiting expression of Mcl1.
Brian J. Ball, Wenbin Xiao, Gautam Borthakur, Le Xuan Truong Nguyen, Melissa Valerio, Avanthika Venkatachalam, Guido Marcucci, Anthony S. Stein, Dung Luong Thai, David N. Cook, Kyle Chan, Sonali Persaud, Ross L. Levine, Omar Abdel-Wahab, Yinon Ben-Neriah, Eytan M. Stein   +15 more
doaj   +1 more source

Yck1 casein kinase I regulates the activity and phosphorylation of Pah1 phosphatidate phosphatase from Saccharomyces cerevisiae. [PDF]

J Biol Chem, 2019
Hassaninasab A, Hsieh LS, Su WM, Han GS, Carman GM.   +4 more
europepmc   +1 more source

Yeast phospholipase C is required for stability of casein kinase I Yck2p and expression of hexose transporters. [PDF]

FEMS Microbiol Lett, 2017
Zhang T, Galdieri L, Hasek J, Vancura A.
europepmc   +1 more source

FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes. [PDF]

Sci Rep, 2016
Kuga T, Sasaki M, Mikami T, Miake Y, Adachi J, Shimizu M, Saito Y, Koura M, Takeda Y, Matsuda J, Tomonaga T, Nakayama Y.   +11 more
europepmc   +1 more source

The casein kinase I family of enzymes

, 1995
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu)
Graves, Paul R.
core   +1 more source

Identification of interacting partners of Discs overgrown in vivo

, 2009
The mutated forms of the Discs overgrown gene causes overproliferation of imaginal discs of Drosophila melanogaster. Somatic mutations in its human counterpart, casein kinase I epsilon, were strongly associated with human breast cancer.
MAREŠOVÁ, Petra
core  

Casein kinase I d/e phosphorylates topoisomerase

, 2008
IIa at serine-1106 and modulates DNA cleavage ...
Belinda Willard, Michael Kinter, Adrian G. Grozav, Kenichi Chikamori, Ronald M. Bukowski, Toshiyuki Kozuki, Ram Ganapathi, Dale R. Grabowski, Anni H. Andersen, Mahrukh K. Ganapathi   +9 more
core  

Correction: Wang et al. Casein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling. <i>Int. J. Mol. Sci.</i> 2023, <i>24</i>, 7034. [PDF]

Int J Mol Sci
Wang B, Zhang J, Zhang D, Lu C, Liu H, Gao Q, Niu T, Yin M, Cui S.   +8 more
europepmc   +1 more source