Results 131 to 140 of about 30,523 (236)

Modular Rh‐Catalyzed Synthesis and Biological Profiling of Diverse Pentafluorobenzenesulfonamide Reactive Fragments

open access: yesChemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
A modular Rh‐catalyzed synthetic approach enabled the preparation of diverse reactive fragments from available substrates. The reactive fragments modified Aurora A kinase via several distinct modification reaction classes. In a complex biological environment, the constellation of modified proteins depended critically on the reactive fragment structure.
Julian Chesti   +8 more
wiley   +1 more source

The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II

open access: yes, 1990
The entire coding sequence of wild-type mouse p53 was expressed in Escherichia coli under control of the PL promoter of bacteriophage lambda. The bacterial p53 protein had identical mobility to p53 from SV3T3 cells on SDS polyacrylamide gels and was ...
Eckhart, W.   +3 more
core  

Characterization of an Epidermal Phosphatase Specific for Filaggrin Phosphorylated by Casein Kinase II

open access: yes, 1988
During cellular remodeling that accompanies cornification of epidermal cells, the highly phosphorylated protein, profilaggrin, is dephosphorylated and proteolytically cleaved to filaggrin, the keratin matrix protein. Using rat filaggrin phosphorylated by
Haugen-Scofield, Julie   +2 more
core   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

Serum-stimulated cell growth causes oscillations in casein kinase II activity

open access: yes, 1989
We have tested the effects of serum-stimulated growth of quiescent WI38 human lung fibroblasts on cellular casein kinase II (CK-II) activity. Using the casein kinase II synthetic substrate RRREEETEEE we find a transient 6-fold elevation in CK-II activity
Carroll, D., Marshak, D. R.
core  

Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity

open access: yes, 2007
Copyright © 2007 by the American Society for Biochemistry and Molecular BiologyStarD10 is a dual specificity lipid transfer protein capable of shuttling phosphatidylcholine and phosphatidylethanolamine between membranes in vitro.
Schoffler, P.   +5 more
core   +1 more source

Retinoic Acid‐Related Orphan Nuclear Receptor Alpha Promotes Cartilage Degeneration in Osteoarthritis by Activating the Wnt/β‐Catenin Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
During the development of OA, elevated RORα in chondrocytes inhibits β‐catenin degradation in the cytoplasm by activating the Wnt/β‐catenin signaling pathway. When β‐catenin protein accumulates excessively in the cytoplasm, it is transferred to the nucleus and binds to the cytosolic TCF/LEF transcriptional complex, which activates downstream target ...
Ruijue Zhu   +9 more
wiley   +1 more source

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo. [PDF]

open access: yesBMC Cancer, 2020
Richter A   +9 more
europepmc   +1 more source

Synergistic stimulation of fibrinogen gelation by casein kinase II and polycationic compounds

open access: yes, 1997
The processes of thrombin-induced gelation of the fibrinogen may be influenced by a variety of factors including phosphorylational state of the fibrinogen.
Kyoungho Suk   +2 more
core   +1 more source

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