Results 111 to 120 of about 24,797 (285)

Inhibition of the Casein-Kinase-1-Epsilon/Delta Prevents Relapse-Like Alcohol Drinking [PDF]

, 2012
Stéphanie Perreau‐Lenz, Valentina Vengeliene, Hamid R. Noori, Emilio Merlo‐Pich, Mauro Corsi, Corrado Corti, Rainer Spanagel   +6 more
openalex   +1 more source

Betaine Promotes Milk Protein Synthesis via Alleviating Oxidative Stress Caused by NEFA in Mammary Epithelial Cells of Dairy Cows

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Betaine alleviated NEFA‐induced oxidative stress, which served as a central mechanistic link between fatty liver and mammary dysfunction, and concurrently improved milk protein synthesis via regulation of the Nrf2‐JAK2/STAT5/mTOR axis. ABSTRACT Background Fatty liver is highly prevalent in dairy cows and poses a significant challenge to the dairy ...
Wenyan Yan, Xinyuan Sun, Huanjie Shi, Zhenwang Li, Wenhui Li, Xiaoxiao Gao, Jihong Dong   +6 more
wiley   +1 more source

Casein Kinases Interact and Stabilize Glucose Sensing Receptors in Yeast

, 2022
Undergraduate ...
Mailloux, Levi, Adams, Sophia, Humble, Julia   +2 more
core  

Identification of signalling cascades involved in red blood cell shrinkage and vesiculation

Bioscience Reports, 2015
Even though red blood cell (RBC) vesiculation is a well-documented phenomenon, notably in the context of RBC aging and blood transfusion, the exact signalling pathways and kinases involved in this process remain largely unknown.
Elena B. Kostova, Boukje M. Beuger, Thomas R.L. Klei, Pasi Halonen, Cor Lieftink, Roderick Beijersbergen, Timo K. van den Berg, Robin van Bruggen   +7 more
doaj   +1 more source

Inhibiting casein kinase 2 overcomes paclitaxel resistance in gastric cancer [PDF]

, 2019
Minkyu Jung, Kyu Hyun Park, Hyun Myong Kim, Tae Soo Kim, Xianglan Zhang, Sun-Mi Park, Seung‐Hoon Beom, Hyo Song Kim, Jae‐Ho Cheong, Hyun Cheol Chung, John Soong, Shu-Chuan Lin, Sun Young Rha   +12 more
openalex   +1 more source

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3866-3884, July 2026.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero, Brigida Boccanegra, Paola Mantuano, Antonietta Mele, Michela De Bellis, Roberta Lenti, Francesca Sanarica, Santa Cirmi, Elena Conte, Ornella Cappellari, Amber E. Sherrard, Ardawna Green, Mira Srinivasa, Marta L. Fiorotto, Annamaria De Luca   +14 more
wiley   +1 more source

Effect of Okadaic Acid On Membrane-protein Phosphorylation In Human Erythrocytes

, 1993
Okadaic acid, penetrating the human erythrocytes, almost completely inhibits P-Ser-protein phosphatase activity, whereas it unaffects Ser/Thr-protein kinase activity (casein kinases CKI and CKII), thus promoting a marked increase of the endogenous Ser ...
CLARI, GIULIO, TESSARIN, CINZIA, V. MORET, M. BELLATO, BORDIN, LUCIANA   +4 more
core   +1 more source

Proteomic and phosphoproteomic analysis of rabies pathogenesis in the clinical canine brain and identification of a kinase inhibitor as a potential repurposed antiviral agent.

PLoS ONE
Rabies is a fatal zoonosis caused by the rabies virus (RABV) that has afflicted humans for thousands of years. RABV infection leads to neurological symptoms and death; however, its pathogenesis in the brain is unclear, which complicates patient care ...
Peerut Chienwichai, Kunjimas Ketsuwan, Boonlert Lumlertdacha, Chanon Fa-Ngoen, Punchaya Supasawat, Rojjanaporn Pulmanausahakul, Promsin Masrinoul, Tipparat Thiangtrongjit, Onrapak Reamtong   +8 more
doaj   +1 more source

Casein Kinase 1 α Phosphorylates the Wnt Regulator Jade-1 and Modulates Its Activity [PDF]

, 2014
Lori Borgal, Markus M. Rinschen, Claudia Dafinger, Sylvia Hoff, Matthäus J. Reinert, Tobias Lamkemeyer, Soeren S. Lienkamp, Thomas Benzing, Bernhard Schermer   +8 more
openalex   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source