Results 101 to 110 of about 4,619 (182)

Isolation of a Protease‐Producing Microbacterium From the Intestinal Tract of Ruditapes philippinarum and Its Probiotic Effects

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Aquatic probiotics are generally recognized as safe and nontoxic live bacterial preparations, primarily sourced from the culturing environment or directly from aquatic organisms. Upon entering the aquatic environment, these probiotics are capable of colonizing both the surface and internal compartments of aquatic organisms, thereby enhancing their ...
Hui Guan, Yaodong Qiu, Mingyue Guan, Sitong Quan, Shang Liu, Yingxu Chen, Haochen Li, Haolin Yu, Lei Fang, Zhongming Huo, Arkadios Dimitroglou   +10 more
wiley   +1 more source

Divergent Fates of Hardjo Leptospires: Early Transcriptomic Response of Leptospira interrogans in an Ovine Dialysis Membrane Chamber Model

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Leptospira interrogans serovar Hardjo and Leptospira borgpetersenii serovar Hardjo are major bovine‐ and ovine‐adapted pathogens that differ markedly in genome content. To investigate early events during host exposure, we compared the survival of both species using an ovine peritoneal dialysis membrane chamber (DMC) model, which exposes leptospires to ...
Klaudia Dubniewicz, Laura Pardyak, Patrycja Walczak, Agnieszka Pietsch-Fulbiszewska, Artur Gurgul, Igor Jasielczuk, Tomasz Szmatoła, Zbigniew J. Arent, Yong-guo Cao   +8 more
wiley   +1 more source

Toxin Production by Aeromonas sobria in Natural Environments: River Water vs. Seawater [PDF]

, 2008
Aeromonas are water-borne pathogens. They are halotolerant, which means that they can survive in environments whose salt content corresponds to that of seawater (3.0% NaCl).
Ansaruzzaman, Mohammad, Banik, Sukalyani, Khan, Rasel, Nakura, Hironori, Okamoto, Keinosuke, Ramamurthy, Thandavarayan, Takahashi, Eizo   +6 more
core   +1 more source

Screening, Purification, and Characterization of Protease Inhibitors From Different Legume Seeds With Cytotoxic and Antimicrobial Effects

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT This study reports the purification and characterization of protease inhibitors (PIs) from three Egyptian legumes: soybean (Glycine max), cowpea (Vigna unguiculata), and chickpea (Cicer arietinum). Their antimicrobial and cytotoxic activities were also assessed.
Mona M. Ibrahim, Andrea Cavallero, Eman R. Zaki, Mohamed R. Rady, Cristiana Sbrana, Morena Gabriele   +5 more
wiley   +1 more source

Mucosal immunization with caseinolytic protease X elicited cross-protective immunity against pneumococcal infection in mice

Experimental Biology and Medicine, 2012
Streptococcus pneumoniae resides on the mucosal surface of the upper respiratory tract and is ready to spread and trigger clinical diseases. Hence the vaccine that can eliminate the nasopharyngeal colonization was thought to be an ideal protective strategy against pneumococcal invasive diseases.
Wen, Zhong, Wenchun, Xu, Hong, Wang, Yuanshuai, Huang, Ju, Cao, Yi, Gong, Xiuyu, Xu, Xun, Min, Yanqing, Zhang, Jie, Dong, Yibing, Yin, Xuemei, Zhang   +11 more
openaire   +2 more sources

Ovarian Aging: Mechanisms, Age‐Related Disorders, and Therapeutic Interventions

MedComm, Volume 6, Issue 12, December 2025.
A comprehensive overview of the molecular mechanisms underlying ovarian aging, its association with age‐related diseases, and potential therapeutic interventions. Ovarian aging involves DNA damage, mitochondrial dysfunction, oxidative stress, telomere attrition, and follicular depletion, driving age‐related infertility, menopause, and multiple systemic
Xingyu Liu, Yuanqu Zhao, Yanzhi Feng, Shixuan Wang, Jinjin Zhang   +4 more
wiley   +1 more source

Dysregulated Fatty Acid Metabolism in Preeclampsia Among Highland Andeans: Insights Into Adaptive and Maladaptive Placental Metabolic Phenotypes

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
Multi‐omic profiling of highland Andeans reveals adaptive fetal haplotypes associated with favorable placental metabolic phenotypes, while preeclampsia is marked by dysregulated fatty acid oxidation and acylcarnitine accumulation across maternal‐placental‐fetal compartments. Metabolomic profiling showed widespread accumulation of medium‐ and long‐chain
Katie A. O'Brien, Lilian Toledo‐Jaldin, Wanjun Gu, Julie A. Houck, Litzi Lazo‐Vega, Valquiria Miranda‐Garrido, Hong W. Yung, Hussna Yasini, Lorna G. Moore, Julie A. Reisz, Tatum S. Simonson, Jonathan Shortt, Margaret Stalker, Angelo D'Alessandro, Colleen G. Julian   +14 more
wiley   +1 more source

Emerging role of Lon protease as a master regulator of mitochondrial functions [PDF]

, 2016
Lon protease is a nuclear-encoded, mitochondrial ATP-dependent protease highly conserved throughout the evolution, crucial for the maintenance of mitochondrial homeostasis.
BORTOLOTTI, Carlo Augusto, COSSARIZZA, Andrea, DE BIASI, SARA, GIBELLINI, Lara, IANNONE, Anna, NASI, Milena, PINTI, Marcello   +6 more
core   +1 more source

A Proteolytic Site‐Directed Affinity Label to Inhibit the Human ATP‐Dependent Protease Caseinolytic Complex XP

ChemBioChem, 2020
AbstractHuman caseinolytic protease component X and P (hClpXP) is a heterooligomeric ATP‐dependent protease. The hClpX subunit catalyzes ATP hydrolysis whereas the hClpP subunit catalyzes peptide bond cleavage. In this study, we generated a peptidyl chloromethyl ketone (dansyl‐FAPAL‐CMK) that inhibited the hClpP subunit through alkylation of the ...
Zhou Sha, Sujatha Chilakala, George Crabill, Iteen Cheng, Yan Xu, Jennifer Fishovitz, Irene Lee   +6 more
openaire   +3 more sources

Proteolysis in milk during experimental Escherichia coli mastitis [PDF]

, 2004
This work consisted of the intramammary infections (IMI) of 8 heifers by high doses of Escherichia coli to study both the proteolytic activity in milk and the resulting peptides. Therefore, a milking kinetic has been followed, and several parameters have
Burvenich, Christian, Duchateau, Luc, HADDADI, K, LAURENT, F, LE ROUX, Y, MOUSSAOUI, F, Vangroenweghe, Frédéric   +6 more
core   +2 more sources