Results 101 to 110 of about 147,909 (161)

Structural studies of Caseinolytic protease 1 from Mycobacterium tuberculosis and Methionyl-tRNA synthetase from Mycobacterium smegmatis

, 2010
Tuberculosis is a severe disease that causes about 2 million deaths every year. It is a worldwide threat and it is estimated that one-third of the world’s population carries the infection. The severe side effects of the present drugs, and the more than 6
Ingvarsson, Henrik
core   +2 more sources

Identification of Potent Modulators of Human Caseinolytic Protease P for the Treatment of Hepatocellular Carcinoma: Molecular Docking, Density Functional Theory Calculation, Molecular Dynamic Simulation Studies, and In vitro Validation

Biomedical and Biotechnology Research Journal
Background: Human caseinolytic protease P (HsClpP) is a mitochondrial protease playing a vital role in mitochondrial protein quality control and represents a promising therapeutic target for hepatocellular carcinoma (HCC).
Chun Wang, Minghui Sha, Weilin Gong, Zili Sun, Dan Xu, Di Wu, Hailei Ji   +6 more
doaj   +1 more source

Caseinolytic protease P (CLPP) activated by ONC201 inhibits proliferation and promotes apoptosis in human epithelial ovarian cancer cells by inducing mitochondrial dysfunction. [PDF]

Ann Transl Med, 2021
Kou X, Ding H, Li L, Chao H.
europepmc   +1 more source

Inibidor de protease

, 2013
Os inibidores de protease evitam a maturação das proteínas virais dentro das partículas de HIVEducação Superior::Ciências da Saúde ...
Howard Hughes Medical Institute (HHMI)
core   +2 more sources

Detection of caseinolytic activity in Fbln5^−/− tissues.

, 2013
(A) a, casein zymography using vaginal extracts from wild-type (WT) and Fbln5−/− (KO) at 1–2 months of age. Arrow indicates caseinolytic activity at 25-kDa. b, corresponding coomassie staining showing equal loading.
Ruth Ann Word (380217), Madhusudhan Budatha (380211), Simone Silva (380212), Masashi Yanagisawa (224823), Teodoro Ignacio Montoya (380213), Ayako Suzuki (380214), Cecilia Karin Wieslander (380216), Hiromi Yanagisawa (380218), Sheena Shah-Simpson (380215)   +8 more
core   +1 more source

Potensi protease bacillus subtilis natto sebagai pengempuk daging [PDF]

, 2006
Kualitas daging yang akan dikonsumsi dapat ditingkatkan dengan pemberian enzim protease. Penelitian ini bertujuan untuk mempelajari pengemupkan daging sapi dengan menggunakan enzim protease dari B subtilis natto (B.natto).
Ferdian, Helmi
core  

Inibidor de protease

, 2016
Os inibidores de protease evitam a maturação das proteínas virais dentro das partículas de HIVEducação Superior::Ciências da Saúde ...
Howard Hughes Medical Institute (HHMI)
core   +1 more source

A report on thermostable alkaline protease producing bacteria from a terrestrial thermal spring

, 2015
1104-1111Five efficient protease producing moderate thermophiles were isolated from Unkeshwar (19°85’ N and 78°25’E) thermal spring located in Nanded district of Maharashtra. The isolates were identified as Bacillus firmus, Bacillus aminivorans, Bacillus
Rathod, Mukundraj G., Pathak, Anupama P.
core  

Development and evaluation of mitochondria-targeted caseinolytic protease (ClpP) agonist chemical probes in in vitro breast cancer models. [PDF]

Med Chem Res
Hao X, Purohit G, Jayasinghe YP, Ronning DR, Khalimonchuk O, Trippier PC.   +5 more
europepmc   +1 more source

The design and synthesis of mycobacterium tuberculosis caseinolytic protease inhibitors

, 2019
A dissertation submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg In fulfillment of the requirements for the Degree of Master of Science May, 2019Tuberculosis (TB) is the main cause of death from a single infectious ...
Shuro, Pious
core