Results 111 to 120 of about 4,619 (182)

Extraction, purification, and activity of protease from the leaves of Moringa oleifera [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
Background: Proteases cleave proteins, thereby providing essential amino acids for protein synthesis, and degrade misfolded and damaged proteins to maintain homeostasis.
Swarnali Banik, Shrutidhara Biswas, Srabani Karmakar   +2 more
doaj   +1 more source

Effect of pH and ionic strength on μ- and m-calpain inhibition by calpastatin [PDF]

, 2005
The objectives of this study were to determine the extent to which pH and ionic strength influence μ- and m-calpain activity and the inhibition of calpains by calpastatin.
Huff-Lonergan, Elisabeth, Huff-Lonergan, Elisabeth, Lonergan, Steven, Lonergan, Steven, Maddock, K., Rowe, L.   +5 more
core   +1 more source

Purification and cDNA cloning of the ovigerous-hair stripping substance (OHSS) contained in the hatch water of an estuarine crab Sesarma haematocheir [PDF]

, 2004
The egg attachment system of an estuarine crab Sesarma haematocheir is formed on the maternal ovigerous hairs just after egg laying, and slips off these hairs just after hatching.
Agata, Kiyokazu, Gusev, Oleg, Hatakeyama, Masatsugu, Ikeda, Hideki, Kobayashi, Chiyoko, Lee, Jae Min, Okochi, Tetsushi, Saigusa, Masayuki, Yamada, Hidenori   +8 more
core   +1 more source

Enterobacterial caseinolytic protease B (ClpB) and ClpB antibodies in adolescents with anorexia nervosa

Journal of Psychiatric Research
Caseinolytic protease B (ClpB) produced by the gut enterobacteria displays anorexigenic effects possibly due to its molecular mimicry with α-melanocyte-stimulating hormone (α-MSH), an anorexigenic neuropeptide. ClpB is known to induce α-MSH cross-reactive antibodies previously associated with eating disorders.
Benjamin Thomas, Nadia Andrea Andreani, Emilie Lahaye, John F. Baines, Beate Herpertz-Dahlmann, Jochen Seitz, Sergueï O. Fetissov   +6 more
openaire   +2 more sources

A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60

The Journal of Clinical Investigation, 2022
Mitochondrial proteostasis, regulated by the mitochondrial unfolded protein response (UPRmt), is crucial for maintenance of cellular functions and survival. Elevated oxidative and proteotoxic stress in mitochondria must be attenuated by the activation of
Rahul Kumar, Ajay K. Chaudhary, Jordan Woytash, Joseph R. Inigo, Abhiram A. Gokhale, Wiam Bshara, Kristopher Attwood, Jianmin Wang, Joseph A. Spernyak, Eva Rath, Neelu Yadav, Dirk Haller, David W. Goodrich, Dean G. Tang, Dhyan Chandra   +14 more
doaj   +1 more source

Preliminary Study on the Production of Extracellular Protease from a Newly Isolated Bacillus sp. (No.1) and the Physical Factors Affecting Its Production [PDF]

, 1997
A thermophilic bacterium isolated from a dumping ground in Sri Petaling, Kuala Lumpur, identified as Bacillus sp. (No.1), was able to grow at 600C and showed proteolytic activity on skim milk agar.
Abdul Razak, Che Nyonya, Basri, Mahiran, Salleh, Abu Bakar, Tang, S. W.   +3 more
core  

Engineering Bacillus pumilus alkaline serine protease to increase its low-temperature proteolytic activity by directed evolution

BMC Biotechnology, 2018
Background Mesophilic alkaline serine proteases from various bacteria have been commercially applied in a range of industries owing to their high catalytic efficiency and wide substrate specificity.
Hong-Yan Zhao, Hong Feng
doaj   +1 more source

Enamel proteins and proteases in Mmp20 and Klk4 null and double‐null mice [PDF]

, 2011
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90347/1/j.1600-0722.2011.00866.x ...
Bartlett, Bartlett, Bartlett, Bartlett, Begue-Kirn, Bourd-Boittin, Boyde, Bronckers, Caterina, Chun, Chun, Fincham, Fincham, Fincham, Fukae, Fukae, Fukae, Fukae, Hart, Hu, Hu, Hu, Hu, Hu, Iwata, Kim, Kobayashi, Krebsbach, Lau, Li, Lu, Nagano, Nanci, Nanci, Ronnholm, Ryu, Ryu, Ryu, Simmer, Simmer, Simmer, Simmer, Simmer, Simmer, Simmer, Simmer, Smith, Smith, Smith, Smith, Suga, Sun, Tye, Uchida, Yamada, Yamakoshi   +55 more
core   +1 more source

Control of substrate gating and translocation into ClpP by channel residues and ClpX binding [PDF]

, 2010
ClpP is a self-compartmentalized protease, which has very limited degradation activity unless it associates with ClpX to form ClpXP or with ClpA to form ClpAP.
Barkow, Bewley, Bewley, Bogyo, Breusing, Brotz-Oesterhelt, Burton, Burton, Farrell, Flynn, Goldberg, Gottesman, Gottesman, Gottesman, Gribun, Grimaud, Groll, Hersch, Ingvarsson, Jenal, Jennings, Joshi, Kang, Kenniston, Kessel, Kim, Kim, Kim, Kirstein, Kwon, Levchenko, Liu, Martin, Martin, Martin, Mary E. Lee, Maurizi, Maurizi, Ortega, Powers, Rabl, Reinstein, Robert T. Sauer, Sauer, Siddiqui, Singh, Singh, Smith, Smith, Song, Sousa, Sousa, Striebel, Szyk, Tania A. Baker, Thompson, Thompson, Wang, Whitby, Yoo, Yu   +60 more
core   +1 more source

Protein purification to analyze AAA+ proteolytic machine in vitro [PDF]

, 2011
The ATP-dependent ClpXP protease of Escherichia coli consists of two subunits, the ClpP subunit, which has the proteolytic activity and the AAA+ motor ClpX, which mechanically unfolds and translocates substrates for ClpP degradation.
Rojas, Diego F.
core   +2 more sources