Results 211 to 220 of about 35,966 (338)

Complement dysregulation in human tauopathies

open access: yesBrain Pathology, EarlyView.
Complement protein and activation product levels were assessed in post‐mortem frontal cortex from three distinct subtypes of Tauopathy: Corticobasal degeneration, globular glial tauopathy, and Pick's disease. Quantification of complement proteins by immunohistochemistry and ELISA showed elevation of key complement proteins (C1q) regulators (FI) and ...
Jacqui Nimmo   +3 more
wiley   +1 more source

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Proteolytic balance is dysregulated in many diseases, with proteases playing critical roles in pathological pathways. A high level of Trypsin‐3 expression has been implicated as a significant mediator of tumour progression and metastasis, and this protease is associated with poor prognosis for patients in various cancers.
Melissa David   +9 more
wiley   +1 more source

Assessment of the molecular mechanisms of drug‐induced hidden cardiotoxicity by a multi‐omics approach: The example of rofecoxib

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Hidden cardiotoxicity is defined as drug‐induced cardiotoxicity that becomes obvious only in the presence of comorbidities. However, the molecular mechanisms of hidden cardiotoxicity are not always known. Therefore, unbiased multi‐omics approaches could assist in revealing regulatory pathways.
Bennet Y. Weber   +12 more
wiley   +1 more source

Circulating Food Allergen‐Specific Antibodies, Beyond IgG4, Are Elevated in Eosinophilic Esophagitis

open access: yesClinical &Experimental Allergy, EarlyView.
Elevated IgG and IgA subclasses to food allergens in eosinophilic esophagitis (EoE) highlight a complex immune response involving antibody production, underscoring the significance of dietary triggers like cow's milk in disease management and potential for personalised therapies.
Manal Bel Imam   +46 more
wiley   +1 more source

Separation of α-, β- and γ-Casein

open access: bronze, 1952
N. J. Hipp   +3 more
openalex   +1 more source

Effects of Farming System on the Rheological Behavior of Rennet-Induced Coagulation in Milk from Skopelos Breed Goats. [PDF]

open access: yesFoods
Kotsiou K   +7 more
europepmc   +1 more source

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