Results 61 to 70 of about 89,609 (343)

Development of a monoclonal antibody to detect αs1-casein in the milk of healthy and mastitis-affected goats [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019
This study aimed to evaluate the expression level of caseins during mastitis of goats. Whole goat caseins were used as primary antigens for mouse immunization.
Ming PANG, Xiong GUAN, Chen-Xiang ZUO, Ming-Jie LIU, Saad REHMAN, Qin-Lei FAN, Ping LU, De-Kun CHEN, Wen-Tao MA   +8 more
doaj   +1 more source

Allergen Risk Assessment for Specific Allergy to Small Ruminant's Milk: Development of Sensitive Immunoassays to Detect Goat's and Sheep's Milk Contaminations in Dairy Food Matrices

Frontiers in Allergy, 2021
Despite a high level of sequence identity between cow's, goat's, and sheep's milk (CM, GM, and SM, respectively) proteins, some patients tolerant to CM are allergic to GM and SM.
Hervé Bernard, Stéphane Hazebrouck, Nicolas Gaiani, Karine Adel-Patient   +3 more
doaj   +1 more source

Exploring Gelatin‐A and Mouse Proline‐Rich Protein 5 as Probes for Wine Polyphenol Analysis by Quartz Crystal Microbalance with Dissipation Monitoring

Advanced Sensor Research, EarlyView.
This study presents a novel strategy for the detection of polyphenols in wine. By combining Quartz Crystal Microbalance with Dissipation Monitoring and original functionalization strategies, Gelatin A from porcine skin and Mouse Proline‐Rich Protein 5, polyphenols are successfully detected directly in wine without any prior sample preparation ...
Giorgia Tori, Mariacristina Gagliardi, Francesco Lunardelli, Chiara Sanmartin, Isabella Taglieri, Gianmarco Alfieri, Margherita Modesti, Domenica Convertino, Andrea Bellincontro, Fabio Mencarelli, Marco Cecchini   +10 more
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

Preferential Binding of Polyphenols in Blackcurrant Extracts with Milk Proteins and the Effects on the Bioaccessibility and Antioxidant Activity of Polyphenols

Foods
Milk proteins are well-known delivery agents; however, there is no clear understanding of the competitive interactions of milk proteins with polyphenols in mixed complex systems. Here, we investigate the preferential competitive interactions of different
Ting Mao, FNU Akshit, Iresha Matiwalage, Subha Sasidharan, Caren Meyn Alvarez, Philip Wescombe, Maneesha S. Mohan   +6 more
doaj   +1 more source

The action of rennin on casein The disruption of thek-casein complex [PDF]

Journal of Dairy Research, 1963
SummaryApproximately 30% of the nitrogen of κ-casein was soluble at pH 4·7 after the protein had been treated with rennin at pH 7 while approximately 10% was soluble in 12% trichloroacetic acid (TCA). The material soluble in 12% TCA appeared at a slower rate initially than did the nitrogen soluble at pH 4·7 but as the reaction proceeded it was released
Beeby, R., Nitschmann, Hs
openaire   +4 more sources

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Variations in Bovine Milk Proteins and Processing Conditions and Their Effect on Protein Digestibility in Humans: A Review of In Vivo and In Vitro Studies

Foods
Bovine milk proteins account for 10% of the global protein supply, which justifies the importance of thoroughly understanding their digestive processes. Extensive research on digestion is being conducted both in vivo and in vitro.
Conor J. Fitzpatrick, Daniela Freitas, Tom F. O’Callaghan, James A. O’Mahony, André Brodkorb   +4 more
doaj   +1 more source

Effect of temperature and pH on the solubility of caseins: environmental influences on the dissociation of α(S)- and β-casein.

Journal of Dairy Science, 2012
Selective precipitation is a common method for the isolation of β-casein, using the different calcium sensitivities of the individual caseins and the selective solubility of β-casein at a low temperature.
A. E. Post, B. Arnold, Jochen Weiss, Jörg Hinrichs   +3 more
semanticscholar   +1 more source