Results 211 to 220 of about 341,145 (337)

Bcl-2 Blocks a Caspase-Dependent Pathway of Apoptosis Activated by Herpes Simplex Virus 1 Infection in HEp-2 Cells [PDF]

, 2000
Verónica Galván, Renato Brandimarti, Joshua Munger, Bernard Roizman   +3 more
openalex   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Effect of Acupotomy Modulation of NLRP3/Caspase-1/GSDMD Pathway on Chondrocyte Pyroptosis in Knee Osteoarthritis. [PDF]

J Pain Res
Wang Y, Chen Y, Yang Y, Zhou Y, Yang Y, Zhu J.   +5 more
europepmc   +1 more source

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

, 2000
Piera Pasinelli, Megan K. Houseweart, Robert H. Brown, Don W. Cleveland   +3 more
openalex   +1 more source

The CXCL10‐CXCR3 Axis Induces Tumor‐Associated Neutrophils to Interfere with CTLs‐Mediated Antitumor Activity in EBV‐Associated Epithelial Cancers

Advanced Science, EarlyView.
Compared with EBV‐negative epithelial cancer cells, EBV‐associated epithelial cancer cells exhibit enhanced secretion of chemokines, including CXCL10 and CCL5, to attract neutrophils. Via the CXCL10‐CXCR3 axis‐mediated positive feedback loop, neutrophils within EBV‐associated epithelial cancer cells are induced to form abundant NETs, which facilitate ...
Dijun Ouyang, Tong Xiang, Yuanyuan Chen, Mengjia Song, Jingjing Zhao, Hao Chen, Si Li, Lifeng Zhang, Chi Xu, Yan Ren, Yong Tao, Qijing Wang, Jia He, Yongqiang Li, Sisi Xie, Yuanyuan Liu, Yan Wang, Xinyi Yang, Jinqi You, Songzuo Xie, Yingzi Li, Desheng Weng, Qiuzhong Pan, Qi Yang, Jianchuan Xia   +24 more
wiley   +1 more source

Repurposed clindamycin suppresses pyroptosis in tumor-associated macrophages through Inhibition of caspase-1. [PDF]

J Exp Clin Cancer Res
Weich A, Berges J, Flamann C, Bitterer K, Singh KP, Chambers D, Lischer C, Lai X, Wolkenhauer O, Berking C, Krönke G, Gupta S, Bruns H, Vera J, Macrophages RG.   +14 more
europepmc   +1 more source

Aven, a Novel Inhibitor of Caspase Activation, Binds Bcl-xL and Apaf-1 [PDF]

, 2000
B CHAU
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Mitochondrial Dysfunction Increases Expression of Endothelin-1 and Induces Apoptosis through Caspase-3 Activation in Rat Cardiomyocytes In Vitro

, 2000
Koichi Yuki, Takashi Miyauchi, Yoshihiko Kakinuma, Nobuyuki Murakoshi, Takahiko Suzuki, Junichi Hayashi, Katsutoshi Goto, Iwao Yamaguchi   +7 more
openalex   +2 more sources

Caspase 3-mediated Cleavage of p21 Associated with the Cyclin A-Cyclin-dependent Kinase 2 Complex Is a Prerequisite for Apoptosis in SK-HEP-1 Cells [PDF]

, 2000
Ying Jin, Kye Jin Yoo, You Hui Lee, Seung Ki Lee   +3 more
openalex   +1 more source