Results 221 to 230 of about 24,095,126 (372)
Aven, a Novel Inhibitor of Caspase Activation, Binds Bcl-xL and Apaf-1 [PDF]
, 2000 B CHAU
openalex +1 more source
Advanced Science, EarlyView.This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni +12 more
wiley +1 more source
Herpes Simplex Virus 1 Blocks Caspase-3-Independent and Caspase-Dependent Pathways to Cell Death
, 1999 Verónica Galván +2 more
openalex +1 more source
Salmonella Exploits Caspase-1 to Colonize Peyer's Patches in a Murine Typhoid Model [PDF]
, 2000 Denise M. Monack +5 more
openalex +1 more source
Advanced Science, EarlyView.In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang +10 more
wiley +1 more source
Caspase 3-mediated Cleavage of p21 Associated with the Cyclin A-Cyclin-dependent Kinase 2 Complex Is a Prerequisite for Apoptosis in SK-HEP-1 Cells [PDF]
, 2000 Ying Jin +3 more
openalex +1 more source
Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source
RBPMS2 can inhibit the NLRP3 / caspase-1 / GSDMD signaling pathway to resist pyroptosis in gastric cancer cells. [PDF]
Sci RepZhang N +6 more
europepmc +1 more source