Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma. [PDF]
PLoS ONE, 2017 Apoptosis plays a dual role in cancer development and malignancy. The role of apoptosis-related caspases in cancer remains controversial, particularly in oral tongue squamous cell carcinoma (OTSCC).
Pei-Feng Liu +11 more
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Apoptosis Regulators Bcl-2 and Caspase-3
Encyclopedia, 2022 Apoptosis, programmed cell death, has a central role in developmental biology and in maintaining the equilibrium of renewing tissues. A founding member of the Bcl-2 family of regulatory proteins for apoptosis is Bcl-2, which is encoded by the BCL2 gene ...
Piret Hussar
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Air-Exposure- and Reoxygenation-Stimulated Expressions of Caspase-3 and Induction of Apoptosis in the Central Nervous System of the Crab Erimacrus isenbeckii [PDF]
CellsAir exposure stress during live transport and subsequent reoxygenation are factors in the development of molecular/pathological and compensatory/adaptive responses.
Elena Kotsyuba, Vyacheslav Dyachuk
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Miltirone induces GSDME-dependent pyroptosis in colorectal cancer by activating caspase 3 [PDF]
HeliyonColorectal cancer (CRC) is a common and malignant tumor, ranking as the third most common cancer in men and the second most common cancer in women. Pyroptosis, a recently described programmed cell death mechanism mediated by the GSDM family, has emerged ...
Guangwei Zheng +3 more
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Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis
Journal of Cell Biology, 2022 Eskandari and Eaves review evidence of caspase-3-regulated protein quality, proliferation, differentiation, and tumorigenic activity in viable cells.
E. Eskandari, C. Eaves
semanticscholar +1 more source
Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity
Cell Death and Disease, 2021 Chemotherapy drug-induced nephrotoxicity limits clinical applications for treating cancers. Pyroptosis, a newly discovered programmed cell death, was recently reported to be associated with kidney diseases.
X. Shen +4 more
semanticscholar +1 more source
Diagnostics, 2021 Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is ...
Aleksandra Mielczarek-Palacz +2 more
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Roles of apoptosis and autophagy in natural rabies infections
Veterinární Medicína, 2022 The aim of this study was to investigate the activity of apoptosis and autophagy in animals (cows, horses, donkeys, dogs and cats) naturally infected with rabies by using immunohistochemistry, immunofluorescence, and qPCR.
M Ozkaraca +3 more
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Molecular Imaging of Apoptosis: The Case of Caspase-3 Radiotracers
International Journal of Molecular Sciences, 2021 The molecular imaging of apoptosis remains an important method for the diagnosis and monitoring of the progression of certain diseases and the evaluation of the efficacy of anticancer apoptosis-inducing therapies.
Lucas Beroske +4 more
semanticscholar +1 more source
The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells. [PDF]
PLoS ONE, 2009 In cystic fibrosis (CF), the most frequent mutant variant of the cystic fibrosis transmembrane conductance regulator (CFTR), F508del-CFTR protein, is misfolded and retained in the endoplasmic reticulum (ER). We previously showed that the unfolded protein
Mathieu Kerbiriou +4 more
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