Results 181 to 190 of about 16,739,924 (339)

Caspase‐3 regulates the migration, invasion and metastasis of colon cancer cells

International Journal of Cancer, 2018
Min Zhou, Xinjian Liu, Zonghai Li, Qian Huang, Fang Li, Chuan-Yuan Li   +5 more
semanticscholar   +1 more source

Herpes Simplex Virus 1 Blocks Caspase-3-Independent and Caspase-Dependent Pathways to Cell Death

, 1999
Verónica Galván, Renato Brandimarti, Bernard Roizman   +2 more
openalex   +1 more source

Caspase‐3 Mediated Neuronal Death After Traumatic Brain Injury in Rats [PDF]

, 2000
Robert S. B. Clark, Patrick M. Kochanek, Simon C. Watkins, Minzhi Chen, C. Edward Dixon, Neal Seidberg, John A. Melick, J. Eric Loeffert, Paula D. Nathaniel, Kun Jin, Steven H. Graham   +10 more
openalex   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Super-Sensitive Chemiluminescent Probe for the Detection of Caspase-3 Activity. [PDF]

Bioconjug Chem
Tannous R, Zhang C, Shabat D.
europepmc   +1 more source

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

Cell, 1997
Hua Zou, W. Henzel, X. Liu, Alexis Lutschg, Xiaodong Wang   +4 more
semanticscholar   +1 more source

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source

Salidroside ameliorates diabetic amyotrophy by targeting Caspase-3 to inhibit apoptosis. [PDF]

Sci Rep
Wang H, Yousaf W, Haseeb A, Wang Z, Zheng J.   +4 more
europepmc   +1 more source

HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4⁺T cells [PDF]

, 2000
Claudia Cicala, James Arthos, A. Rubbert, Sara Selig, Kathryn F. Wildt, Oren J. Cohen, Anthony S. Fauci   +6 more
openalex   +1 more source

Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao, Fangling Hong, Yao Dong, Yong Fu, Yunong Ma, Xuedi Sun, Junfeng Zhang, Jiangning Chen, Zhen Huang   +8 more
wiley   +1 more source