Results 181 to 190 of about 476,553 (353)

Effects of 8-week Exercise on Bcl-2, Bax, Caspase-8, Caspase-3 and HSP70 in Mouse Gastrocnemius Muscle [PDF]

, 2010
Ki-Bum Kim, Yong An Kim, Jung-Jun Park
openalex   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Selective Up-Regulation of Phosphatidylinositol 3′-Kinase Activity in Th2 Cells Inhibits Caspase-8 Cleavage at the Death-Inducing Complex: A Mechanism for Th2 Resistance from Fas-Mediated Apoptosis [PDF]

, 1999
Arun S. Varadhachary, Marcus E. Peter, Somia N. Perdow, Peter H. Krammer, Padmini Salgame   +4 more
openalex   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Curcumin induces apoptosis through FAS and FADD, in caspase-3-dependent and -independent pathways in the N18 mouse-rat hybrid retina ganglion cells

, 2009
Chung
openalex   +2 more sources

Anti-apoptotic Activity of Ginsenoside Rb₁in Hydrogen Peroxide-treated Chondrocytes: Stabilization of Mitochondria and the Inhibition of Caspase-3 [PDF]

, 2012
Ji-Young Na, Sokho Kim, Kibbeum Song, Kyu-Hee Lim, Gee-Wook Shin, Jong‐Hoon Kim, Bumseok Kim, Young‐Bae Kwon, Jungkee Kwon   +8 more
openalex   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Apoptosis induction of human leukemia cells by Streptomyces sp. SY-103 metabolites through activation of caspase-3 and inactivation of Akt

, 2009
Choi
openalex   +2 more sources

Correction to: Inhibition of cathepsin B by caspase-3 inhibitors blocks programmed cell death in Arabidopsis [PDF]

, 2018
Yuan Ge, Y-M. Cai, L. Bonneau, Vitalyi Rotari, Antoine Danon, Edward A. McKenzie, Hazel McLellan, Lukas Mach, Patrick Gallois   +8 more
openalex   +1 more source

Supplementary Figure and Table Legends from Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a

, 2023
Jacqueline C. Shultz, Rachel W. Goehe, Dayanjan S. Wijesinghe, Charuta Murudkar, Amy J. Hawkins, Jerry W. Shay, John D. Minna, Charles E. Chalfant   +7 more
openalex   +1 more source