Results 201 to 210 of about 16,739,924 (339)

Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2 [PDF]

, 2000
Wen‐Hsiung Chan, Jau‐Song Yu, Shiaw‐Der Yang   +2 more
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway. [PDF]

Int J Mol Med
Liang S, Zhu Z, Tang Y, Zhou S, Xiao M, Gong X, Ye K.   +6 more
europepmc   +1 more source

Rapid caspase‐3 activation during apoptosis revealed using fluorescence‐resonance energy transfer

, 2000
Lorraine Tyas, Victoria A. Brophy, Andrew J. Pope, A. Jennifer Rivett, Jeremy M. Tavaré   +4 more
openalex   +1 more source

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

Advanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang, Guofu Zhang, Yizhou Zhu, Jingcheng Wang, Xinmin Feng, Wenyong Fei, Jihang Dai, Le Hu, Yi Zhang, Jun Cai, Binjia Ruan, Yue Jin, Fanhao Wei, Gang Lu, Dongan Wang, Jason Pui Yin Cheung, Graham Ka Hon Shea, Hao Chen, Kelvin Wai Kwok Yeung, Lei Wang, Yongxiang Wang   +20 more
wiley   +1 more source

Activation of human endogenous retroviruses by Sox proteins induces cell apoptosis via the caspase-3 pathway. [PDF]

Front Microbiol
Hossain MJ, Monde N, Sasaki H, Nyame P, Amesimeku WAO, Terasawa H, Matsumura S, Matsui T, Tsutsuki H, Maeda Y, Sawa T, Monde K.   +11 more
europepmc   +1 more source

Ribozyme-Mediated Inhibition of Caspase-3 Protects Cerebellar Granule Cells from Apoptosis Induced by Serum–Potassium Deprivation [PDF]

, 2000
Basil A. Eldadah, Renée F. Ren, Alan I. Faden   +2 more
openalex   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Cleavage of CAD by caspase-3 determines the cancer cell fate during chemotherapy. [PDF]

Nat Commun
Ma J, Zhao J, Zhang C, Tan J, Cheng A, Niu Z, Lin Z, Pan G, Chen C, Ding Y, Zhong M, Zhuang Y, Xiong Y, Zhou H, Zhou S, Xu M, Ye W, Li F, Song Y, Wang Z, Hong X.   +20 more
europepmc   +1 more source

Degradation of the Type I Inositol 1,4,5‐Trisphosphate Receptor by Caspase‐3 in SH‐SY5Y Neuroblastoma Cells Undergoing Apoptosis [PDF]

, 2000
Lise Sofie Haug, S. Ivar Walaas, Anne Carine Østvold   +2 more
openalex   +1 more source