Results 291 to 300 of about 16,739,924 (339)

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

Advanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos, Xavier Barceló, M. Gabriella Chiariello, Irene Sanz, Amaia Iturrospe, Arantxa Arbe, J. Alberto Ortega, Siewert J. Marrink, Aitziber L. Cortajarena, Zaida Álvarez, Ivan R. Sasselli   +10 more
wiley   +1 more source

Oxypeucedanin alleviates cisplatin-induced intestinal toxicity through impairing caspase-3/gasdermin E signaling. [PDF]

J Vet Med Sci
Wang R, Gao F, Hao L, Zhang J, Chen Z, Song D, Gao F, He W, Zhao K, Guan J.   +9 more
europepmc   +1 more source

A “3+2” Cooperation Pattern of Amphipathic AIE Phototheranostic System for Multimodal Image‐Guided Synergistic Type I/II Photodynamic‐Photothermal Therapy

Advanced Science, EarlyView.
A “3+2” cooperation pattern of amphipathicity PTA (named TDTMSB) with aggregation‐induced emission (AIE) features is designed and synthesized to perform near‐infrared I/II fluorescence imaging, photoacoustic imaging, photothermal imaging, and Type I/II photodynamic therapy (PDT)‐photothermal therapy (PTT) synergistic phototherapy for malignant tumors ...
Haijun Ma, Yibo An, Yuanyuan Han, Feifan Zhao, Yunfei Zuo, Guokang He, Zhixiang Lu, Ryan T. K. Kwok, Jianwei Sun, Jacky W. Y. Lam, Yen Wei, Ben Zhong Tang   +11 more
wiley   +1 more source

Let-7a microRNA modulates caspase-3-dependent apoptosis in melanoma cells treated with dabrafenib and trametinib combination. [PDF]

Ir J Med Sci
Keser M, Atmaca H.
europepmc   +1 more source

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

Correction: The absence of Pitx3 results in postnatal loss of dopamine neurons and is associated with an increase in the pro-apoptotic Bcl2 factor Noxa and cleaved caspase 3. [PDF]

Cell Death Dis
Kouwenhoven WM, Robinson EJ, Hamberg D, von Oerthel L, Smidt MP, van der Heide LP.   +5 more
europepmc   +1 more source

AS-IV Attenuates Oxidative Stress-Induced Apoptosis in Zebrafish via Modulation of the AKT/NRF2/HO-1/Caspase-3 Signaling Axis. [PDF]

Molecules
Dai J, E Z, Bi Y, Yin Z, Wang Y, Wang X, Jia X, Zou B.   +7 more
europepmc   +1 more source

Inhibition of Caspase-3/GSDME Pathway-Mediated Pyroptosis of Renal Tubular Epithelial Cells by Dagliflozin in the Pathogenesis of Diabetic Kidney Disease and Study of Its Mechanism. [PDF]

Diabetes Metab Syndr Obes
Jiang H, Gao M, Liu J, Yang L, Liu L.
europepmc   +1 more source

Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML. [PDF]

Cancer Biol Ther
Zhang Z, Lin X, Yang Y, Wang X, Wang Y, Huang X, Hong M, Gao W, He H, You MJ, Yang Y, Kong G.   +11 more
europepmc   +1 more source

Phytochemical analysis and biological effects of Zingiber cassumunar extract and three phenylbutenoids: targeting NF-κB, Akt/MAPK, and caspase-3 pathways. [PDF]

BMC Complement Med Ther
Gundom T, Sukketsiri W, Panichayupakaranant P.   +2 more
europepmc   +1 more source