Results 321 to 330 of about 16,586,228 (338)
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Flow Cytometric Detection of Activated Caspase-3
2008Apoptosis (programmed cell death) is an active process that plays a critical role in multiple biologic processes from embryologic development, to lymphocyte development and selection, and homeostasis. The two major mechanisms of cell death are referred to as the intrinsic and extrinsic pathways.
Richard Fox, Martine Aubert
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Caspase-3-mediated cleavage of PICOT in apoptosis
Biochemical and Biophysical Research Communications, 2013Mammalian protein kinase C-interacting cousin of thioredoxin (PICOT) is a multi-domain mono-thiol glutaredoxin that is involved in several signal transduction pathways and is necessary for cell growth and metastasis. Here, we demonstrate that PICOT is a cleavage substrate of the apoptosis-related protein caspase-3.
Hirohiko Shibayama +6 more
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Caspase-3 expression in lichen planus
Menoufia Medical Journal, 2016Objective: The aim of this study was to examine keratinocyte apoptosis and caspase-3 expression in lichen planus (LP). Background: Caspase-3 expression level in LP lesions is considered a reliable marker of apoptosis, which is frequently found in LP, but the pathways leading to apoptosis are unknown.
Eman A Zaky +2 more
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Caspase‐3 in ultraviolet radiation cataract
Acta Ophthalmologica, 2014AbstractPurpose To determine the evolution of active caspase‐3 protein expression in normal lens and in the lens exposed to low dose UVR‐300 nm.Methods Forty Sprague‐Dawley rats were unilaterally exposed in vivo to 1 kJ/m2 UVR 300 nm for 15 minutes. At 0.5, 8, 16, and 24 hours after the UVR exposure, the exposed and non‐exposed lenses were removed and ...
P Söderberg +3 more
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Quantification of Active Caspase 3 in Apoptotic Cells
Analytical Biochemistry, 2000We describe an enzyme-linked immunosorbent assay (ELISA) for quantifying relative amounts of active caspase 3 in apoptotic cells. Covalent modification of caspase 3 active sites with a biotinylated inhibitor differentiates active from latent caspases. Capture on an ELISA plate with an antibody specific for caspase 3 makes the assay specific for caspase
Mark J. Schendel +17 more
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Caspase-3 Induced Apoptosis in Transgenic Zebrafish
Biotechnology Letters, 2006Zebrafish is an attractive model organism for studying apoptosis development because of its genetic accessibility. Here we describe the induction of clonally derived apoptosis in transgenic zebrafish expressing mouse caspase-3 (CASP3) under control of the zebrafish beta-actin promoter (betap).
Biplab Sarkar +5 more
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The riddle of mitochondrial caspase-3 from liver
Apoptosis, 2009Caspase-3 is one of the main executors of apoptosis. Its zymogen procaspase-3 was localized to cytosol, mitochondria and nuclei. The subcellular location of procaspase-3 in liver was reported by several studies to be either cytosolic or cytosolic and mitochondrial.
Dušan Šuput +2 more
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GSDME mediates caspase-3-dependent pyroptosis in gastric cancer.
Biochemical and Biophysical Research Communications - BBRC, 2018Yubin Wang +5 more
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Design and Synthesis of Photochemically Controllable Caspase‐3
Angewandte Chemie International Edition, 2004Masayuki Endo +3 more
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