Results 81 to 90 of about 18,682,677 (305)

Assessment of apoptotic mediators in different periodontal plights: apoptosis markers in periodontal diseases

Dental Journal
Background: Highly expressed apoptosis markers in an inflammatory condition were observed following periodontal breakdown with obscure lineaments. Purpose: This trial aimed to assess the gingival crevicular fluid (GCF) level of caspase-3, -8, -9, and ...
Asem Mohammed Kamel Ali, Bahaa M. Badr, Abdullah I. Ali, Mohamoud A. Mizer, Ahmed M. Abdelrahman, Asmaa Rashad Ali, Abdel-Moneim M. I. Ghorab, Mohammed G. M. El Sherbeny, Azza A. Althoqapy   +8 more
doaj   +1 more source

Caspase-3-Responsive, Fluorogenic Bivalent Bottlebrush Polymers

Controlling the access of proteases to cleavable peptides placed at specific locations within macromolecular architectures represents a powerful strategy for biologically responsive materials design.
Bin Liu (5899), Hadiqa Zafar (4335619), Hung V.-T. Nguyen (2885066), Jeremiah A. Johnson (1316577)   +3 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Protective Effects of <em>Chlorella</em>-Derived Peptide Against UVC-Induced Cytotoxicity through Inhibition of Caspase-3 Activity and Reduction of the Expression of Phosphorylated FADD and Cleaved PARP-1 in Skin Fibroblasts

Molecules, 2012
UVC irradiation induces oxidative stress and leads to cell death through an apoptotic pathway. This apoptosis is caused by activation of caspase-3 and formation of poly(ADP-ribose) polymerase-1 (PARP-1). In this study, the underlying mechanisms<em>
Jong Yuh Cherng, Mei Fen Shih
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Tracheal cryopreservation: caspase-3 immunoreactivity in tracheal epithelium and in mixed glands

Brazilian Journal of Medical and Biological Research, 2009
Cryopreservation has an immunomodulating effect on tracheal tissue as a result of class II antigen depletion due to epithelium exfoliation. However, not all epithelium is detached.
A. Sotres-Vega, M. Baltazares-Lipp, J. Villalba-Caloca, M.O. Gaxiola-Gaxiola, J.A. Santibañez-Salgado, J.R. Olmos-Zúñiga, R. Jasso-Victoria   +6 more
doaj   +1 more source

Caspase-3 activity increases following QLT-0276 treatment in paired females.

, 2017
Result of the caspase-3 activity assay showing that compared to a DMSO-treated control (left) the activity of caspase-3 of S. mansoni increased significantly (p = 0.01) in paired females treated with 100 μM QLT-0276 (right) as determined ...
Steffen Hahnel (437327), Christoph G. Grevelding (107094), Marion Morel (154333), Colette Dissous (107088), Katia Cailliau (107091), Verena Gelmedin (342441)   +5 more
core   +1 more source

Caspase inhibitors affect the kinetics and dimensions of tracheary elements in xylogenic Zinnia (Zinnia elegans) cell cultures [PDF]

, 2010
Background The xylem vascular system is composed of fused dead, hollow cells called tracheary elements (TEs) that originate through trans-differentiation of root and shoot cambium cells. TEs undergo autolysis as they differentiate and mature.
Elena T Iakimova, Ernst J Woltering, Qian Tian, Twumasi, P., Schel Jan HN, Emons, A.M.C., Wim van Ieperen, Olaf van Kooten, van Ieperen Wim, van Kooten, O., van Ieperen, W., Iakimova, E.T., van Kooten Olaf, Qian, T., Emons Anne, Schel, J.H.N., Peter Twumasi, Tian Qian, Iakimova Elena T, Woltering, E.J., Anne Emons, Kooten, O., van, Ieperen, W., van, Anne MieC Emons, Twumasi Peter, Woltering Ernst J, Jan HN Schel   +26 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Assessment of the Protective Effect of Myricetin in Chemically Induced Oral Squamous Cell Carcinoma in Hamsters [PDF]

SINAI International Scientific Journal
Introduction: Scientific studies indicate that biologically active compounds are present in medicinal plants, and antioxidant agents are effective in treating several diseases, including cancer.
Nadia Radi, Doaa Habba, Seham Hallool, Hanaa Abd Elsamia   +3 more
doaj   +1 more source