Results 231 to 240 of about 8,801,929 (295)

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

Angewandte Chemie, EarlyView.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam, Juyoung Yoon   +10 more
wiley   +2 more sources

Redox-sensitive and inflammatory pathway modulation by Chrysin confers protection against aflatoxin B1-induced hepato-renal damage. [PDF]

Mycotoxin Res
Zeybek E, Kart A, Özmen Ö.
europepmc   +1 more source

2‐Azaazulenium Hemicyanine Dyes for NIR‐II Multimodal Imaging and Combined Phototherapy

Angewandte Chemie, EarlyView.
A strategically engineered class of 2‐azaazulenium hemicyanines is developed, featuring bright fluorescence in the second near‐infrared (NIR‐II) window and multifunctional performance. SWJT‐OCH3 shows type I/II reactive oxygen species (ROS) generation and excellent photothermal activity.
Min Peng, Bing‐Ya Wang, Hai Xu, Qiang Wang, Rong‐Dan Xiao, Rui Tan, Yu Peng, Ya‐Wen Wang, Juyoung Yoon   +8 more
wiley   +2 more sources

Limonin alleviates pyroptosis and inflammatory responses in cardiomyocytes of myocardial ischemia-reperfusion mice by inhibiting the caspase-3/GSDME pathway. [PDF]

Front Immunol
Li J, Li Z, Wang P, Jiang Z.
europepmc   +1 more source

Nitrogen Mustard Disrupts Bioenergetics and Activates Oxidative Stress-Induced Cell Death Pathways in Human Keratinocytes. [PDF]

Chem Res Toxicol
Jan YH, Michniak-Kohn B, Joseph LB, Laskin DL, Laskin JD.   +4 more
europepmc   +1 more source

Progress in the Treatment of Ulcerative Colitis by Targeting NLRP3 Inflammasome. [PDF]

Drug Des Devel Ther
Chen J, Zhang E, Qian X, Shang X, Yu J, Luo J, Hao W.   +6 more
europepmc   +1 more source

Jaceosidin inhibits cell viability and induces apoptosis in non-small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways. [PDF]

Oncol Lett
Cao X, Ma C, Wang X, Wang C, Shen L, Wei J, Yang R, Li Y, He X, Chen L.   +9 more
europepmc   +1 more source

Alternative splicing of Spodoptera exigua caspase-5 is involved in regulating host-cell apoptosis induced by AcMNPV infection

Journal of Integrative Agriculture
Qianlong Yu, Xinyu Wu, Minghui Wang, Jie Li, Guiling Zheng, Changyou Li   +5 more
openaire   +1 more source

Investigation of Sevoflurane-Induced Apoptotic Damage in Human Cardiomyocytes and the Protective Efficacy of Ascorbic Acid. [PDF]

Medicina (Kaunas)
Aydoğan E, Övey İS, Karahan O.
europepmc   +1 more source