Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source
Caspase-8: Arbitrating Life and Death in the Innate Immune System. [PDF]
CellsGupta S +8 more
europepmc +1 more source
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
, 2000 Yunyi Wei +8 more
openalex +1 more source
Superoxide During Reperfusion Contributes to Caspase-8 Expression and Apoptosis After Transient Focal Stroke [PDF]
, 2001 Yuiko Morita‐Fujimura +3 more
openalex +1 more source
Advanced Science, EarlyView.This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li +9 more
wiley +1 more source
Macrophage caspase-8 inhibition accelerates necrotic core expansion in atheroma plaque in mice. [PDF]
Front ImmunolPilot T +8 more
europepmc +1 more source
Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis
, 2000 Claus Belka +9 more
openalex +1 more source
Contrasting Effects of IG20 and Its Splice Isoforms, MADD and DENN-SV, on Tumor Necrosis Factor α-induced Apoptosis and Activation of Caspase-8 and -3 [PDF]
, 2001 Adeeb Al-Zoubi +6 more
openalex +1 more source
Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model
Advanced Science, EarlyView.Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis +7 more
wiley +1 more source
B Cell Receptor Cross-Linking Triggers a Caspase-8- Dependent Apoptotic Pathway That Is Independent of the Death Effector Domain of Fas-Associated Death Domain Protein [PDF]
, 2001 Laurence Besnault +5 more
openalex +1 more source