Results 271 to 280 of about 5,538,011 (302)
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Science Signaling, 2002
Investigation of two siblings with an autoimmune lymphoproliferative syndrome (ALPS) has resulted in the identification of novel functions for caspase-8. The caspases, a family of cysteine proteases, play a key role in executing apoptosis, a cell suicide process that counters cell proliferation to achieve a homeostatic balance.
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Investigation of two siblings with an autoimmune lymphoproliferative syndrome (ALPS) has resulted in the identification of novel functions for caspase-8. The caspases, a family of cysteine proteases, play a key role in executing apoptosis, a cell suicide process that counters cell proliferation to achieve a homeostatic balance.
openaire +2 more sources
Caspase-8 is a player in pyroptosis
Science, 2018Immunology The activation of certain pattern-recognition receptors by pathogen-associated molecular patterns results in the formation of inflammasome complexes. Inflammasome complexes can initiate both the maturation of inflammatory cytokines and pyroptotic cell death via the caspase-mediated cleavage of gasdermin D (GSDMD).
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Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
Cell, 2020Min Zheng, Rajendra Karki
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Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis
Immunity, 2020Bart Tummers +2 more
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ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
Cell, 2018Ricard Garcia-Carbonell +2 more
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Identification of a new caspase homologue: caspase-14
Cell Death and Differentiation, 1998Marc Van De Craen +2 more
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Emerging roles of caspase-3 in apoptosis
Cell Death and Differentiation, 1999Reiner U Janicke, Janicke Reiner U
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